HSPB2 and CKM

Data Source:
BioGRID (two hybrid)

		HSPB2	CKM
Description		heat shock protein family B (small) member 2	creatine kinase, M-type
Image
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol	Extracellular Space Cytosol
	Molecular Function	Structural Constituent Of Eye Lens Protein Binding Enzyme Activator Activity	Creatine Kinase Activity Protein Binding ATP Binding Kinase Activity
	Biological Process	Response To Unfolded Protein Regulation Of Catalytic Activity	Creatine Metabolic Process Phosphorylation Phosphocreatine Biosynthetic Process
Pathways			Creatine metabolism
Drugs			Creatine (Diaminomethyl-Methyl-Amino)-Acetic Acid D-arginine Phosphocreatine
Diseases
GWAS			Alzheimer's disease or family history of Alzheimer's disease ( 30617256) Alzheimer's disease or HDL levels (pleiotropy) ( 30805717) Blood protein levels ( 29875488) Body mass index ( 26426971) Body mass index (age>50) ( 26426971) Body mass index x age interaction ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Creatine kinase levels in statin users ( 25214527) Intelligence (MTAG) ( 29326435)
Interacting Genes		108 interacting genes: A1CF A2M ABCC9 ABCD4 ACAA2 ACTA1 ACTB ACTC1 ACTG1 AGAP11 ALDH2 ALDOA ASAH1 ATP5F1A ATP6V1E1 B2M BAG3 BEX2 BEX4 BGN BICRAL C1QA CAPZA2 CEP19 CKM CLK4 CMYA5 CRYAA CRYAB CRYGC CTSB CTSD CYP1B1 DCTN1 DCTN6 DDIT4 DMPK DUSP1 EEF1A1 EIF4A2 ENKD1 ENO1 ENO3 ETFA FHL2 FLNC GAPDH GARS1 HADHB HNRNPD HOXB9 HSPB3 HSPB8 KANK2 LGALS1 LMO1 LMO3 MAPKAPK5 MB MCCC2 MDH1 MISP MLF2 MT-CO1 MT-CO2 MT-CO3 MYBPC3 MYH6 MYOM2 MYOZ2 NARS1 NDUFA13 NDUFA6 NT5DC2 PARVA PATZ1 PGM1 PKP2 POGZ PPM1K PRR35 RFPL3 RPL11 RPL36A RPL36AL RPS11 RPS6KA5 RYR2 SDF2 SDHA SLC2A1 SNCA SNU13 SNX18 TATDN1 TCAP THEMIS2 THUMPD2 TLX3 TNNI3 TTN TXNIP UBL5 VEZF1 WDR1 WWOX YPEL3 ZNF335	14 interacting genes: ASB9 CBLC CKB CKMT1A CKMT1B FHL2 HSPB2 MYOC MYOM2 NOS1AP TRIM54 TRIM55 TRIM63 YWHAQ
Entrez ID		3316	1158
HPRD ID		03712	00426
Ensembl ID		ENSG00000170276	ENSG00000104879
Uniprot IDs		A8KAH6 Q16082	B2R892 P06732
PDB IDs		6F2R	1I0E
Enriched GO Terms of Interacting Partners?
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