TSEN54 and MRPL38

Data Source:
BioGRID (two hybrid)

		TSEN54	MRPL38
Description		tRNA splicing endonuclease subunit 54	mitochondrial ribosomal protein L38
Image		No pdb structure
GO Annotations	Cellular Component	TRNA-intron Endonuclease Complex Nucleoplasm Nucleolus	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Large Ribosomal Subunit
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	TRNA-type Intron Splice Site Recognition And Cleavage TRNA Splicing, Via Endonucleolytic Cleavage And Ligation MRNA Processing	Mitochondrial Translational Elongation Mitochondrial Translational Termination
Pathways		tRNA processing in the nucleus	Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination
Drugs
Diseases		Pontocerebellar hypoplasia
GWAS		Deep white matter hyperintensities ( 32517579) FEV1 ( 30804560) Lung function (FEV1) ( 28166213) Lung function (FEV1/FVC) ( 30804560) Lung function (FVC) ( 30804560) Lung function in never smokers (high FEV1 vs average FEV1) ( 26423011) Lung function in never smokers (low FEV1 vs high FEV1) ( 26423011) Platelet count ( 32888494) Plateletcrit ( 32888494) Sight-threatening diabetic retinopathy in type 2 diabetes ( 26188370)
Interacting Genes		21 interacting genes: BRCA1 CCDC57 CLP1 CSNK2B GOLGA6L9 IRF4 KPNA5 KRT31 LHX3 LHX4 LMO2 MCPH1 MRPL38 NAA10 NCKIPSD NFKBID RINT1 TRIM23 TRIML2 TSEN2 ZMYND12	21 interacting genes: ARHGAP9 BAG3 BEX2 CCDC120 CENATAC CSNK2A1 DOCK8 ENKD1 ERCC6 ERG28 GADD45GIP1 GOLGA6A HSPB3 LONRF1 MKRN3 MRPL18 MYOZ3 PPP1R18 PRIM1 RALY TSEN54
Entrez ID		283989	64978
HPRD ID		12291	14758
Ensembl ID		ENSG00000182173	ENSG00000204316
Uniprot IDs		Q7Z6J9	Q96DV4
PDB IDs			3J7Y 3J9M 5OOL 5OOM 6I9R 6NU2 6NU3 6VLZ 6VMI 6ZS9 6ZSA 6ZSB 6ZSC 6ZSD 6ZSE 6ZSG
Enriched GO Terms of Interacting Partners?
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