KLHL20 and C20orf85

Data Source:
BioGRID (two hybrid)

		KLHL20	C20orf85
Description		kelch like family member 20	chromosome 20 open reading frame 85
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Golgi Apparatus Trans-Golgi Network Cytosol Actin Cytoskeleton PML Body Axon Dendrite Cul3-RING Ubiquitin Ligase Complex Perinuclear Region Of Cytoplasm
	Molecular Function	Actin Binding Ubiquitin-protein Transferase Activity Protein Binding Interferon-gamma Binding	Protein Binding
	Biological Process	Golgi To Endosome Transport Cytoskeleton Organization Protein Transport Protein Ubiquitination Response To Interferon-alpha Negative Regulation Of Apoptotic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Post-translational Protein Modification Protein K33-linked Ubiquitination
Pathways		Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Feeling miserable ( 29500382)	Advanced age-related macular degeneration ( 26691988) Obesity-related traits ( 23251661)
Interacting Genes		41 interacting genes: ACTA1 ARHGEF12 ATG9A BCL6 BEX1 BEX2 C1orf216 C20orf85 C21orf58 CEP126 CIDEC CLCNKA COL8A1 CORO7 CRK CRMP1 DUSP21 ECT2 ENKD1 EPAS1 ERG28 GBP2 HR IVNS1ABP KLHL38 LRIF1 LUC7L2 MTNR1A NEDD9 NTAQ1 PIN1 PML PRMT6 RANBP3 RECK SLC13A5 STK16 SUV39H1 TFAP2D TNPO2 USP20	22 interacting genes: ACTN3 ALKBH7 ASPG CABP2 CACNB3 CASK CNOT2 DTX2 EFHC1 FHL2 KLHL2 KLHL20 KRTAP19-6 KRTAP3-1 KRTAP6-2 KRTAP8-1 LCN2 MAD2L2 OIP5 PFDN5 RBPMS TTC19
Entrez ID		27252	128602
HPRD ID		13918	12787
Ensembl ID		ENSG00000076321	ENSG00000124237
Uniprot IDs		Q9Y2M5	Q9H1P6
PDB IDs		5YQ4 6GY5
Enriched GO Terms of Interacting Partners?
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