KLHL20 and TNPO2

Data Source:
BioGRID (two hybrid)

		KLHL20	TNPO2
Description		kelch like family member 20	transportin 2
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Golgi Apparatus Trans-Golgi Network Cytosol Actin Cytoskeleton PML Body Axon Dendrite Cul3-RING Ubiquitin Ligase Complex Perinuclear Region Of Cytoplasm	Nucleus Cytoplasm
	Molecular Function	Actin Binding Ubiquitin-protein Transferase Activity Protein Binding Interferon-gamma Binding	Protein Binding Nuclear Localization Sequence Binding Nuclear Import Signal Receptor Activity
	Biological Process	Golgi To Endosome Transport Cytoskeleton Organization Protein Transport Protein Ubiquitination Response To Interferon-alpha Negative Regulation Of Apoptotic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Post-translational Protein Modification Protein K33-linked Ubiquitination	Protein Import Into Nucleus
Pathways		Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Feeling miserable ( 29500382)	Diffuse large B-cell lymphoma or multiple sclerosis ( 31407831)
Interacting Genes		41 interacting genes: ACTA1 ARHGEF12 ATG9A BCL6 BEX1 BEX2 C1orf216 C20orf85 C21orf58 CEP126 CIDEC CLCNKA COL8A1 CORO7 CRK CRMP1 DUSP21 ECT2 ENKD1 EPAS1 ERG28 GBP2 HR IVNS1ABP KLHL38 LRIF1 LUC7L2 MTNR1A NEDD9 NTAQ1 PIN1 PML PRMT6 RANBP3 RECK SLC13A5 STK16 SUV39H1 TFAP2D TNPO2 USP20	52 interacting genes: A1CF APIP BEND7 BIRC7 BIRC8 BLMH C12orf40 C1orf94 CAMK2B CAMK2D CAMK2G CCDC158 CRYAB CTAG1A CTAG1B ELAVL1 EXOC5 FH FTO FUCA2 GCH1 GSC2 KLHL2 KLHL20 KLHL3 KRT75 KRTAP8-1 NME1 NUP98 NXF1 OTX2 PACSIN3 PDLIM7 PIK3CD PINX1 PNMA5 POU6F2 PRMT8 PYCR1 RAN RBM45 RPL4 RPRD1B SERTAD3 SF1 TBX2 TCL1B TERF1 THAP6 TRIM8 ZBTB32 ZC2HC1C
Entrez ID		27252	30000
HPRD ID		13918	04301
Ensembl ID		ENSG00000076321	ENSG00000105576
Uniprot IDs		Q9Y2M5	A0A024R7F7 O14787 Q05D48 Q4LE60
PDB IDs		5YQ4 6GY5
Enriched GO Terms of Interacting Partners?
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