DAPP1 and TNFAIP1

Data Source:
BioGRID (two hybrid)

		DAPP1	TNFAIP1
Description		dual adaptor of phosphotyrosine and 3-phosphoinositides 1	TNF alpha induced protein 1
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Plasma Membrane	Nucleus Cytoplasm Endosome Cul3-RING Ubiquitin Ligase Complex
	Molecular Function	Protein Binding Phospholipid Binding Phosphatidylinositol-3,4,5-trisphosphate Binding Phosphatidylinositol-3,4-bisphosphate Binding	Ubiquitin-protein Transferase Activity Protein Binding Small GTPase Binding Identical Protein Binding
	Biological Process	Protein Dephosphorylation Signal Transduction	Apoptotic Process Immune Response Cell Migration Protein Ubiquitination Negative Regulation Of Rho Protein Signal Transduction Stress Fiber Assembly Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of DNA Replication Protein Homooligomerization
Pathways		Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
Drugs		Inositol 1,3,4,5-Tetrakisphosphate
Diseases
GWAS		Red cell distribution width ( 32888494)	Blood protein levels ( 29875488) Low density lipoprotein cholesterol levels ( 29403010) Osteoprotegerin levels ( 25080503)
Interacting Genes		23 interacting genes: BTK CNDP2 ERBB3 FAIM FCHSD2 FXN GSTCD HSD3B7 HSPA1A LCK LYN MAP4K1 MGARP MYLIP PLAGL2 PLCG1 PLCG2 RBP7 RPL23 SRC TM4SF19 TNFAIP1 ZNHIT1	31 interacting genes: ARMC7 ARNT CAPN7 CARD9 CDC37 CSNK2B DAPP1 EPHA2 EPM2AIP1 EXOSC5 HAT1 HEXIM2 KCTD10 KCTD13 KDM1A LNX1 NTAQ1 NXF1 POLR1C PRKAG1 PSMA1 RHOA RHOB RIN3 SMARCB1 STK16 SUV39H1 SVIL TRIM54 ZDHHC17 ZMYND19
Entrez ID		27071	7126
HPRD ID		05773	01856
Ensembl ID		ENSG00000070190	ENSG00000109079
Uniprot IDs		J3KNB3 Q9UN19	Q13829
PDB IDs		1FAO 1FB8
Enriched GO Terms of Interacting Partners?
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