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PRKD2 and PDLIM7
Data Source:
BioGRID
(two hybrid)
PRKD2
PDLIM7
Description
protein kinase D2
PDZ and LIM domain 7
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Golgi Apparatus
Cytosol
Plasma Membrane
Stress Fiber
Ruffle
Nucleoplasm
Cytosol
Adherens Junction
Focal Adhesion
Actin Cytoskeleton
Z Disc
Filamentous Actin
Molecular Function
Protein Kinase Activity
Protein Serine/threonine Kinase Activity
Calcium-dependent Protein Kinase C Activity
Protein Kinase C Binding
Protein Binding
ATP Binding
Metal Ion Binding
Actin Binding
Protein Binding
Metal Ion Binding
Muscle Alpha-actinin Binding
Biological Process
Angiogenesis
Positive Regulation Of Endothelial Cell Proliferation
Adaptive Immune Response
Protein Phosphorylation
Cell Adhesion
Cell Death
Positive Regulation Of Endothelial Cell Migration
Peptidyl-serine Phosphorylation
Peptidyl-threonine Phosphorylation
Sphingolipid Biosynthetic Process
Positive Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway
Positive Regulation Of Interleukin-2 Production
Positive Regulation Of Interleukin-8 Production
Positive Regulation Of CREB Transcription Factor Activity
Positive Regulation Of Peptidyl-serine Phosphorylation
Intracellular Signal Transduction
Cellular Response To Vascular Endothelial Growth Factor Stimulus
Positive Regulation Of Endothelial Cell Chemotaxis By VEGF-activated Vascular Endothelial Growth Factor Receptor Signaling Pathway
Positive Regulation Of Blood Vessel Endothelial Cell Migration
Positive Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway
Positive Regulation Of Angiogenesis
Positive Regulation Of Cell Adhesion
Positive Regulation Of Transcription By RNA Polymerase II
Protein Autophosphorylation
Vascular Endothelial Growth Factor Receptor Signaling Pathway
T Cell Receptor Signaling Pathway
Positive Regulation Of T Cell Receptor Signaling Pathway
Positive Regulation Of DNA-binding Transcription Factor Activity
Positive Regulation Of NF-kappaB Transcription Factor Activity
Endothelial Tube Morphogenesis
Positive Regulation Of ERK1 And ERK2 Cascade
Protein Kinase D Signaling
Positive Regulation Of Histone Deacetylase Activity
Positive Regulation Of Intracellular Signal Transduction
Positive Regulation Of DNA Biosynthetic Process
Positive Regulation Of Endothelial Cell Chemotaxis
Ossification
Receptor-mediated Endocytosis
Axon Guidance
Heart Development
Actin Cytoskeleton Organization
Positive Regulation Of Osteoblast Differentiation
Muscle Structure Development
Pathways
Sphingolipid de novo biosynthesis
RET signaling
Drugs
Diseases
GWAS
Chronic lymphocytic leukemia (
18758461
28165464
)
Coronary artery disease (
29212778
)
Eosinophil counts (
32888494
)
Heel bone mineral density (
30598549
)
Post bronchodilator FEV1 (
26634245
)
Primary sclerosing cholangitis (
23603763
27992413
)
Coronary artery disease (
29212778
)
Waist-to-hip ratio adjusted for BMI (
26426971
)
Waist-to-hip ratio adjusted for BMI (age <50) (
26426971
)
Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) (
26426971
)
Interacting Genes
17 interacting genes:
CASK
DST
GLRX3
GORASP1
GRIP1
HDAC7
HEY1
IFNAR1
MTF2
PDLIM7
PFDN1
PSG3
RARB
RRBP1
RXRA
SNRNP70
TGOLN2
62 interacting genes:
ABI2
AP5B1
BAG3
BSG
CATSPER1
CCDC185
DDX6
DGCR6
DNER
ENKD1
FAM214B
FAM71C
FAM90A1
FNDC11
FRS3
GEM
GFAP
GPATCH2L
HEY2
HNRNPD
HNRNPF
HSF2BP
HSPB7
IL16
IQGAP1
KANK2
MDM2
NUDT10
OTUD6A
PAK5
PARVG
PCBP1
PHF1
PIN1
PLEKHN1
PRKCA
PRKCB
PRKCZ
PRKD2
PSMF1
RASGEF1B
RET
RPP25
SCNM1
SH2B2
SH3BP2
SLAIN1
SMURF1
SPP1
TCF19
TNPO2
TP53
TPM2
TRAF2
TRAF3
TSG101
TSGA10IP
UBE2I
UBQLN4
WWP2
ZMYND11
ZNF165
Entrez ID
25865
9260
HPRD ID
09523
10436
Ensembl ID
ENSG00000105287
ENSG00000196923
Uniprot IDs
Q9BZL6
Q9NR12
PDB IDs
2COA
3BGM
4NNX
4NNY
2Q3G
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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