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PRKD2 and SNRNP70
Data Source:
BioGRID
(two hybrid)
PRKD2
SNRNP70
Description
protein kinase D2
small nuclear ribonucleoprotein U1 subunit 70
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Golgi Apparatus
Cytosol
Plasma Membrane
Nucleus
Nucleoplasm
Spliceosomal Complex
U1 SnRNP
Nuclear Speck
U2-type Prespliceosome
Molecular Function
Protein Kinase Activity
Protein Serine/threonine Kinase Activity
Calcium-dependent Protein Kinase C Activity
Protein Kinase C Binding
Protein Binding
ATP Binding
Metal Ion Binding
RNA Binding
MRNA Binding
Protein Binding
SnRNA Binding
U1 SnRNA Binding
Biological Process
Angiogenesis
Positive Regulation Of Endothelial Cell Proliferation
Adaptive Immune Response
Protein Phosphorylation
Cell Adhesion
Cell Death
Positive Regulation Of Endothelial Cell Migration
Peptidyl-serine Phosphorylation
Peptidyl-threonine Phosphorylation
Sphingolipid Biosynthetic Process
Positive Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway
Positive Regulation Of Interleukin-2 Production
Positive Regulation Of Interleukin-8 Production
Positive Regulation Of CREB Transcription Factor Activity
Positive Regulation Of Peptidyl-serine Phosphorylation
Intracellular Signal Transduction
Cellular Response To Vascular Endothelial Growth Factor Stimulus
Positive Regulation Of Endothelial Cell Chemotaxis By VEGF-activated Vascular Endothelial Growth Factor Receptor Signaling Pathway
Positive Regulation Of Blood Vessel Endothelial Cell Migration
Positive Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway
Positive Regulation Of Angiogenesis
Positive Regulation Of Cell Adhesion
Positive Regulation Of Transcription By RNA Polymerase II
Protein Autophosphorylation
Vascular Endothelial Growth Factor Receptor Signaling Pathway
T Cell Receptor Signaling Pathway
Positive Regulation Of T Cell Receptor Signaling Pathway
Positive Regulation Of DNA-binding Transcription Factor Activity
Positive Regulation Of NF-kappaB Transcription Factor Activity
Endothelial Tube Morphogenesis
Positive Regulation Of ERK1 And ERK2 Cascade
Protein Kinase D Signaling
Positive Regulation Of Histone Deacetylase Activity
Positive Regulation Of Intracellular Signal Transduction
Positive Regulation Of DNA Biosynthetic Process
Positive Regulation Of Endothelial Cell Chemotaxis
MRNA Splicing, Via Spliceosome
Regulation Of ATPase Activity
Regulation Of RNA Splicing
Positive Regulation Of MRNA Splicing, Via Spliceosome
Negative Regulation Of Protein Refolding
Negative Regulation Of Chaperone-mediated Autophagy
Pathways
Sphingolipid de novo biosynthesis
mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS
Chronic lymphocytic leukemia (
18758461
28165464
)
Coronary artery disease (
29212778
)
Eosinophil counts (
32888494
)
Heel bone mineral density (
30598549
)
Post bronchodilator FEV1 (
26634245
)
Primary sclerosing cholangitis (
23603763
27992413
)
Electrocardiogram morphology (amplitude at temporal datapoints) (
32916098
)
Systolic blood pressure (
30224653
)
Interacting Genes
17 interacting genes:
CASK
DST
GLRX3
GORASP1
GRIP1
HDAC7
HEY1
IFNAR1
MTF2
PDLIM7
PFDN1
PSG3
RARB
RRBP1
RXRA
SNRNP70
TGOLN2
46 interacting genes:
APP
ARSF
CASP3
CDC42
CDKL3
CEP63
CHERP
CLK2
CRP
CTDP1
DDX17
GEMIN2
GTPBP2
HNRNPA2B1
HTATSF1
IL32
IL7R
LRP1
MYC
NUDT21
PRKD2
PRMT5
PRPF40A
RASGRF1
RELA
RNF11
SCAF11
SHBG
SKIL
SMAD1
SMAD2
SMAD3
SMAD4
SMAD5
SMAD9
SMURF2
SNRPC
SRPK1
SRPK2
SRRM4
SRSF1
SRSF10
SRSF2
TOP1
WBP4
ZRANB2
Entrez ID
25865
6625
HPRD ID
09523
01617
Ensembl ID
ENSG00000105287
ENSG00000104852
Uniprot IDs
Q9BZL6
A0A024QZD5
P08621
Q9UFS1
PDB IDs
2COA
3BGM
4NNX
4NNY
2L5I
2L5J
3CW1
3PGW
4PJO
4PKD
6QX9
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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