PDLIM7 and TNPO2

Data Source:
BioGRID (two hybrid)

		PDLIM7	TNPO2
Description		PDZ and LIM domain 7	transportin 2
Image			No pdb structure
GO Annotations	Cellular Component	Stress Fiber Ruffle Nucleoplasm Cytosol Adherens Junction Focal Adhesion Actin Cytoskeleton Z Disc Filamentous Actin	Nucleus Cytoplasm
	Molecular Function	Actin Binding Protein Binding Metal Ion Binding Muscle Alpha-actinin Binding	Protein Binding Nuclear Localization Sequence Binding Nuclear Import Signal Receptor Activity
	Biological Process	Ossification Receptor-mediated Endocytosis Axon Guidance Heart Development Actin Cytoskeleton Organization Positive Regulation Of Osteoblast Differentiation Muscle Structure Development	Protein Import Into Nucleus
Pathways		RET signaling
Drugs
Diseases
GWAS		Coronary artery disease ( 29212778) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Diffuse large B-cell lymphoma or multiple sclerosis ( 31407831)
Interacting Genes		62 interacting genes: ABI2 AP5B1 BAG3 BSG CATSPER1 CCDC185 DDX6 DGCR6 DNER ENKD1 FAM214B FAM71C FAM90A1 FNDC11 FRS3 GEM GFAP GPATCH2L HEY2 HNRNPD HNRNPF HSF2BP HSPB7 IL16 IQGAP1 KANK2 MDM2 NUDT10 OTUD6A PAK5 PARVG PCBP1 PHF1 PIN1 PLEKHN1 PRKCA PRKCB PRKCZ PRKD2 PSMF1 RASGEF1B RET RPP25 SCNM1 SH2B2 SH3BP2 SLAIN1 SMURF1 SPP1 TCF19 TNPO2 TP53 TPM2 TRAF2 TRAF3 TSG101 TSGA10IP UBE2I UBQLN4 WWP2 ZMYND11 ZNF165	52 interacting genes: A1CF APIP BEND7 BIRC7 BIRC8 BLMH C12orf40 C1orf94 CAMK2B CAMK2D CAMK2G CCDC158 CRYAB CTAG1A CTAG1B ELAVL1 EXOC5 FH FTO FUCA2 GCH1 GSC2 KLHL2 KLHL20 KLHL3 KRT75 KRTAP8-1 NME1 NUP98 NXF1 OTX2 PACSIN3 PDLIM7 PIK3CD PINX1 PNMA5 POU6F2 PRMT8 PYCR1 RAN RBM45 RPL4 RPRD1B SERTAD3 SF1 TBX2 TCL1B TERF1 THAP6 TRIM8 ZBTB32 ZC2HC1C
Entrez ID		9260	30000
HPRD ID		10436	04301
Ensembl ID		ENSG00000196923	ENSG00000105576
Uniprot IDs		Q9NR12	A0A024R7F7 O14787 Q05D48 Q4LE60
PDB IDs		2Q3G
Enriched GO Terms of Interacting Partners?
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