SNRNP70 and GTPBP2

Data Source:
BioGRID (two hybrid)

		SNRNP70	GTPBP2
Description		small nuclear ribonucleoprotein U1 subunit 70	GTP binding protein 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex U1 SnRNP Nuclear Speck U2-type Prespliceosome	Extracellular Region Platelet Alpha Granule Lumen
	Molecular Function	RNA Binding MRNA Binding Protein Binding SnRNA Binding U1 SnRNA Binding	Translation Elongation Factor Activity GTPase Activity Protein Binding GTP Binding Identical Protein Binding
	Biological Process	MRNA Splicing, Via Spliceosome Regulation Of ATPase Activity Regulation Of RNA Splicing Positive Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of Protein Refolding Negative Regulation Of Chaperone-mediated Autophagy	Platelet Degranulation Translational Elongation Biological_process
Pathways		mRNA Splicing - Major Pathway	Platelet degranulation
Drugs
Diseases
GWAS		Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Systolic blood pressure ( 30224653)	Adult body size ( 32376654) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		46 interacting genes: APP ARSF CASP3 CDC42 CDKL3 CEP63 CHERP CLK2 CRP CTDP1 DDX17 GEMIN2 GTPBP2 HNRNPA2B1 HTATSF1 IL32 IL7R LRP1 MYC NUDT21 PRKD2 PRMT5 PRPF40A RASGRF1 RELA RNF11 SCAF11 SHBG SKIL SMAD1 SMAD2 SMAD3 SMAD4 SMAD5 SMAD9 SMURF2 SNRPC SRPK1 SRPK2 SRRM4 SRSF1 SRSF10 SRSF2 TOP1 WBP4 ZRANB2	12 interacting genes: CLK2 GPN3 KDM1A NXF1 PICK1 PLEKHF2 PRMT5 PRMT6 PSMB1 SNRNP70 SUV39H1 TXN2
Entrez ID		6625	54676
HPRD ID		01617	08465
Ensembl ID		ENSG00000104852	ENSG00000172432
Uniprot IDs		A0A024QZD5 P08621 Q9UFS1	A0A024RD30 A8K2K2 Q9BX10
PDB IDs		2L5I 2L5J 3CW1 3PGW 4PJO 4PKD 6QX9
Enriched GO Terms of Interacting Partners?
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