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ARIH1 and CRY1
Data Source:
BioGRID
(enzymatic study)
ARIH1
CRY1
Description
ariadne RBR E3 ubiquitin protein ligase 1
cryptochrome circadian regulator 1
Image
No pdb structure
GO Annotations
Cellular Component
Ubiquitin Ligase Complex
Nucleus
Cytoplasm
Cytosol
Cajal Body
Nuclear Body
SCF Ubiquitin Ligase Complex
Cul2-RING Ubiquitin Ligase Complex
Cul3-RING Ubiquitin Ligase Complex
Cul4A-RING E3 Ubiquitin Ligase Complex
Lewy Body
Nucleus
Cytoplasm
Mitochondrion
Molecular Function
Ubiquitin-protein Transferase Activity
Protein Binding
Zinc Ion Binding
Ubiquitin-like Protein Transferase Activity
Ubiquitin Conjugating Enzyme Binding
Ubiquitin Protein Ligase Binding
Ubiquitin Protein Ligase Activity
DNA Binding
Double-stranded DNA Binding
Deoxyribodipyrimidine Photo-lyase Activity
DNA (6-4) Photolyase Activity
Protein Binding
Blue Light Photoreceptor Activity
Protein Kinase Binding
Phosphatase Binding
Nuclear Hormone Receptor Binding
Histone Deacetylase Binding
E-box Binding
FAD Binding
Biological Process
Protein Polyubiquitination
Ubiquitin-dependent Protein Catabolic Process
Protein Ubiquitination
Protein Phosphopantetheinylation
Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Negative Regulation Of Transcription By RNA Polymerase II
Gluconeogenesis
DNA Damage Induced Protein Phosphorylation
Circadian Rhythm
Response To Light Stimulus
Blue Light Signaling Pathway
Response To Activity
Protein-chromophore Linkage
Lipid Storage
Negative Regulation Of Protein Ubiquitination
Positive Regulation Of Protein Ubiquitination
Response To Insulin
Circadian Regulation Of Gene Expression
Response To Glucagon
Glucose Homeostasis
Regulation Of Circadian Rhythm
Negative Regulation Of Circadian Rhythm
Entrainment Of Circadian Clock By Photoperiod
Negative Regulation Of Gluconeogenesis
Negative Regulation Of G Protein-coupled Receptor Signaling Pathway
Negative Regulation Of Transcription, DNA-templated
Regulation Of DNA Damage Checkpoint
Negative Regulation Of Glucocorticoid Receptor Signaling Pathway
Negative Regulation Of Glucocorticoid Secretion
Pathways
ISG15 antiviral mechanism
Circadian Clock
Drugs
Diseases
GWAS
Morning person (
30696823
)
Interacting Genes
17 interacting genes:
CCNE1
CDKN1B
CRY1
DCUN1D1
EIF4E2
HSPB1
PLD1
RBX1
SEC31A
UBC
UBE2D1
UBE2D3
UBE2E2
UBE2L3
UBE2L6
UBE2N
VAV2
26 interacting genes:
ARIH1
ARNTL
BHLHE41
CBLB
CLOCK
CSNK1E
DELEC1
FBXL3
GRN
KRTAP4-12
LTBP4
MDFI
NPAS2
NR1D2
PER1
PER2
PER3
PLSCR1
PPP2R1B
PPP2R5D
PPP2R5E
SNRPD3
TIMELESS
TRAF2
USP2
USP7
Entrez ID
25820
1407
HPRD ID
05730
09050
Ensembl ID
ENSG00000166233
ENSG00000008405
Uniprot IDs
Q9Y4X5
A2I2P0
Q16526
PDB IDs
1WD2
2M9Y
4KBL
4KC9
5TTE
5UDH
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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