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CRY1 and PER1
Data Source:
BioGRID
(affinity chromatography technology)
HPRD
(in vitro, in vivo, two hybrid)
CRY1
PER1
Description
cryptochrome circadian regulator 1
period circadian regulator 1
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Mitochondrion
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Molecular Function
DNA Binding
Double-stranded DNA Binding
Deoxyribodipyrimidine Photo-lyase Activity
DNA (6-4) Photolyase Activity
Protein Binding
Blue Light Photoreceptor Activity
Protein Kinase Binding
Phosphatase Binding
Nuclear Hormone Receptor Binding
Histone Deacetylase Binding
E-box Binding
FAD Binding
Transcription Regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
Transcription Corepressor Binding
Protein Binding
Kinase Binding
Chromatin DNA Binding
Ubiquitin Protein Ligase Binding
E-box Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Gluconeogenesis
DNA Damage Induced Protein Phosphorylation
Circadian Rhythm
Response To Light Stimulus
Blue Light Signaling Pathway
Response To Activity
Protein-chromophore Linkage
Lipid Storage
Negative Regulation Of Protein Ubiquitination
Positive Regulation Of Protein Ubiquitination
Response To Insulin
Circadian Regulation Of Gene Expression
Response To Glucagon
Glucose Homeostasis
Regulation Of Circadian Rhythm
Negative Regulation Of Circadian Rhythm
Entrainment Of Circadian Clock By Photoperiod
Negative Regulation Of Gluconeogenesis
Negative Regulation Of G Protein-coupled Receptor Signaling Pathway
Negative Regulation Of Transcription, DNA-templated
Regulation Of DNA Damage Checkpoint
Negative Regulation Of Glucocorticoid Receptor Signaling Pathway
Negative Regulation Of Glucocorticoid Secretion
Negative Regulation Of Transcription By RNA Polymerase II
Regulation Of Sodium Ion Transport
Circadian Rhythm
Entrainment Of Circadian Clock
Posttranscriptional Regulation Of Gene Expression
Circadian Regulation Of Gene Expression
Regulation Of Hair Cycle
Regulation Of Circadian Rhythm
Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Entrainment Of Circadian Clock By Photoperiod
Histone H3 Acetylation
Histone H4 Acetylation
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of JNK Cascade
Response To CAMP
Histone H3 Deacetylation
Circadian Regulation Of Translation
Regulation Of Cytokine Production Involved In Inflammatory Response
Regulation Of P38MAPK Cascade
Negative Regulation Of Glucocorticoid Receptor Signaling Pathway
Pathways
Circadian Clock
Circadian Clock
Drugs
Diseases
GWAS
Morning person (
30696823
)
HDL cholesterol levels (
32203549
)
High light scatter reticulocyte percentage of red cells (
32888494
)
Interacting Genes
26 interacting genes:
ARIH1
ARNTL
BHLHE41
CBLB
CLOCK
CSNK1E
DELEC1
FBXL3
GRN
KRTAP4-12
LTBP4
MDFI
NPAS2
NR1D2
PER1
PER2
PER3
PLSCR1
PPP2R1B
PPP2R5D
PPP2R5E
SNRPD3
TIMELESS
TRAF2
USP2
USP7
19 interacting genes:
CCDC57
CRY1
CRY2
CSNK1D
CSNK1E
CSNK1G2
CSNK2B
DELEC1
GPRASP1
HIF1A
LTB4R2
PER2
PER3
PNMA1
RBPMS
RIPOR2
TIMELESS
TNS2
TRIP6
Entrez ID
1407
5187
HPRD ID
09050
03774
Ensembl ID
ENSG00000008405
ENSG00000179094
Uniprot IDs
A2I2P0
Q16526
O15534
PDB IDs
1UL6
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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