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TAB3 and CEP57L1
Data Source:
BioGRID
(two hybrid)
TAB3
CEP57L1
Description
TGF-beta activated kinase 1 (MAP3K7) binding protein 3
centrosomal protein 57 like 1
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Cytosol
Plasma Membrane
Endosome Membrane
Extracellular Exosome
Cellular_component
Cytoplasm
Centrosome
Microtubule
Molecular Function
Protein Binding
Ubiquitin Binding
Metal Ion Binding
Molecular_function
Protein Binding
Microtubule Binding
Identical Protein Binding
Gamma-tubulin Binding
Biological Process
Activation Of MAPK Activity
Stimulatory C-type Lectin Receptor Signaling Pathway
MyD88-dependent Toll-like Receptor Signaling Pathway
I-kappaB Kinase/NF-kappaB Signaling
JNK Cascade
Negative Regulation Of Autophagy
Fc-epsilon Receptor Signaling Pathway
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Positive Regulation Of NF-kappaB Transcription Factor Activity
Nucleotide-binding Oligomerization Domain Containing Signaling Pathway
Interleukin-1-mediated Signaling Pathway
Biological_process
Pathways
NOD1/2 Signaling Pathway
FCERI mediated NF-kB activation
TAK1 activates NFkB by phosphorylation and activation of IKKs complex
activated TAK1 mediates p38 MAPK activation
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
TNFR1-induced NFkappaB signaling pathway
CLEC7A (Dectin-1) signaling
TICAM1,TRAF6-dependent induction of TAK1 complex
Interleukin-1 signaling
IRAK2 mediated activation of TAK1 complex
TRAF6-mediated induction of TAK1 complex within TLR4 complex
Alpha-protein kinase 1 signaling pathway
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
Drugs
Diseases
GWAS
Apolipoprotein A1 levels (
32203549
)
HDL cholesterol levels (
32203549
)
Midgestational circulating levels of PCBs (
28235828
)
Prostate cancer (
23535732
)
Interacting Genes
10 interacting genes:
CEP57L1
IKBKG
MAP3K7
MAP3K7CL
OGT
PIN1
PPIL3
TAB1
TRAF2
TRAF6
84 interacting genes:
AKT1
ALOX5
AP1M1
ARNT2
BRCA1
BYSL
CALCOCO2
CARD9
CBY2
CCDC102B
CCDC136
CCDC57
CDR2
CEP44
CEP55
CEP63
CEP70
CFAP206
DISC1
DVL3
DYDC1
ELOA
EXOC8
FAM161A
FAM9B
GADD45G
GOLGA1
GOLGA2
GRIPAP1
HAUS1
HDDC3
HGS
IKZF1
KATNAL1
KIFC3
KLC3
KLC4
KRT13
KRT19
KRT31
KRT38
KRT40
LENG1
LMO1
LMO3
LZTS2
MAGEA1
MAGEA2B
MCC
MDFI
MEOX2
MFAP1
MID2
MORF4L1
MTUS2
MYO15B
NEFL
NOTCH1
NUP62
PATJ
PICK1
PKN1
PNMA5
PPL
PRDM6
RAD51D
RINT1
ROPN1
SNAP47
SNAPC3
TAB3
TFIP11
TRAF2
TRAPPC2L
TRIM54
TRIP6
TSGA10
TXLNA
TXLNB
VPS28
YES1
ZGPAT
ZNF572
ZNF655
Entrez ID
257397
285753
HPRD ID
06738
10792
Ensembl ID
ENSG00000157625
ENSG00000183137
Uniprot IDs
Q8N5C8
E5RFY4
Q8IYX8
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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