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NUP62 and RANBP2
Data Source:
HPRD
(in vitro)
NUP62
RANBP2
Description
nucleoporin 62
RAN binding protein 2
Image
GO Annotations
Cellular Component
Spindle Pole
Nuclear Envelope
Annulate Lamellae
Nuclear Pore
Nucleoplasm
Cytoplasm
Centrosome
Nuclear Membrane
Host Cell
Nuclear Pore Central Transport Channel
Mitotic Spindle
Flemming Body
Ribonucleoprotein Complex
Nuclear Envelope
Annulate Lamellae
Nuclear Pore
Nucleoplasm
Cytoplasm
Mitochondrion
Cytosol
Membrane
Nuclear Membrane
Nuclear Inclusion Body
Intracellular Membrane-bounded Organelle
Host Cell
Nuclear Pore Cytoplasmic Filaments
Nuclear Pore Nuclear Basket
Cytoplasmic Periphery Of The Nuclear Pore Complex
Molecular Function
Chromatin Binding
Protein Binding
Phospholipid Binding
Structural Constituent Of Nuclear Pore
Kinesin Binding
Signaling Receptor Complex Adaptor Activity
Hsp70 Protein Binding
SH2 Domain Binding
Ubiquitin Binding
Protein-containing Complex Binding
PTB Domain Binding
Hsp90 Protein Binding
RNA Binding
Peptidyl-prolyl Cis-trans Isomerase Activity
GTPase Activator Activity
Protein Binding
Cyclosporin A Binding
SUMO Transferase Activity
Small GTPase Binding
Protein-containing Complex Binding
Metal Ion Binding
Biological Process
Regulation Of Glycolytic Process
RNA Export From Nucleus
MRNA Export From Nucleus
TRNA Export From Nucleus
Protein Import Into Nucleus
Mitotic Metaphase Plate Congression
Centrosome Cycle
Mitotic Centrosome Separation
Cell Surface Receptor Signaling Pathway
Spermatogenesis
Cell Aging
Cell Death
Negative Regulation Of Cell Population Proliferation
Regulation Of Signal Transduction
Viral Process
Protein Sumoylation
Viral Transcription
Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Regulation Of Protein Import Into Nucleus
Negative Regulation Of Apoptotic Process
Negative Regulation Of Programmed Cell Death
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Negative Regulation Of MAP Kinase Activity
Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Positive Regulation Of Mitotic Nuclear Division
Positive Regulation Of Transcription, DNA-templated
Regulation Of Ras Protein Signal Transduction
Negative Regulation Of Ras Protein Signal Transduction
Positive Regulation Of Centriole Replication
Regulation Of Mitotic Spindle Organization
Regulation Of Gene Silencing By MiRNA
Intracellular Transport Of Virus
Centriole Assembly
Regulation Of Cellular Response To Heat
Positive Regulation Of Mitotic Cytokinetic Process
Positive Regulation Of Protein Localization To Centrosome
Protein Peptidyl-prolyl Isomerization
Response To Amphetamine
Regulation Of Glycolytic Process
Regulation Of Gluconeogenesis
MRNA Export From Nucleus
TRNA Export From Nucleus
Protein Folding
NLS-bearing Protein Import Into Nucleus
Viral Process
Protein Sumoylation
Viral Transcription
Positive Regulation Of Glucokinase Activity
Positive Regulation Of GTPase Activity
Centrosome Localization
Regulation Of Gene Silencing By MiRNA
Intracellular Transport Of Virus
Regulation Of Cellular Response To Heat
Pathways
ISG15 antiviral mechanism
Transport of the SLBP independent Mature mRNA
Transport of the SLBP Dependant Mature mRNA
Transport of Mature mRNA Derived from an Intronless Transcript
Transport of Mature mRNA derived from an Intron-Containing Transcript
Rev-mediated nuclear export of HIV RNA
Transport of Ribonucleoproteins into the Host Nucleus
NS1 Mediated Effects on Host Pathways
Viral Messenger RNA Synthesis
NEP/NS2 Interacts with the Cellular Export Machinery
Regulation of Glucokinase by Glucokinase Regulatory Protein
Nuclear import of Rev protein
Vpr-mediated nuclear import of PICs
snRNP Assembly
SUMOylation of DNA damage response and repair proteins
SUMOylation of ubiquitinylation proteins
Nuclear Pore Complex (NPC) Disassembly
Regulation of HSF1-mediated heat shock response
SUMOylation of SUMOylation proteins
SUMOylation of chromatin organization proteins
SUMOylation of RNA binding proteins
SUMOylation of DNA replication proteins
SUMOylation of DNA replication proteins
Transcriptional regulation by small RNAs
Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)
tRNA processing in the nucleus
HCMV Early Events
HCMV Late Events
Postmitotic nuclear pore complex (NPC) reformation
ISG15 antiviral mechanism
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Transport of the SLBP independent Mature mRNA
Transport of the SLBP Dependant Mature mRNA
Transport of Mature mRNA Derived from an Intronless Transcript
Transport of Mature mRNA derived from an Intron-Containing Transcript
Rev-mediated nuclear export of HIV RNA
Transport of Ribonucleoproteins into the Host Nucleus
NS1 Mediated Effects on Host Pathways
Viral Messenger RNA Synthesis
NEP/NS2 Interacts with the Cellular Export Machinery
Regulation of Glucokinase by Glucokinase Regulatory Protein
Nuclear import of Rev protein
Vpr-mediated nuclear import of PICs
snRNP Assembly
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
SUMOylation of DNA damage response and repair proteins
SUMOylation of ubiquitinylation proteins
Nuclear Pore Complex (NPC) Disassembly
Regulation of HSF1-mediated heat shock response
SUMOylation of SUMOylation proteins
SUMOylation of chromatin organization proteins
SUMOylation of RNA binding proteins
SUMOylation of DNA replication proteins
SUMOylation of DNA replication proteins
Transcriptional regulation by small RNAs
Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)
RHO GTPases Activate Formins
tRNA processing in the nucleus
Mitotic Prometaphase
HCMV Early Events
HCMV Late Events
EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS
Attention deficit hyperactivity disorder (
29325848
)
Beard thickness (
26926045
)
Monobrow thickness (
26926045
)
Scalp hair shape (
26926045
)
Interacting Genes
91 interacting genes:
ABI2
ADAM15
AGR3
ARFIP2
ATF7IP2
ATXN7
BFSP1
BLOC1S6
C14orf119
C1orf216
CAVIN3
CCDC121
CCDC146
CCDC150
CCDC153
CCHCR1
CENPU
CEP57L1
CLIC1
CRCT1
DDX3X
DGCR6
DPPA3
DTNB
DYNLT1
FABP3
GOPC
GORASP2
GTF2E2
HAUS1
HGS
HSF2
HSF4
HSPB11
IDH1
IFT20
IK
IKBIP
IPO5
ISCU
KANSL1
KIFC3
KLHL32
KPNA1
KPNA2
KPNB1
KRT1
KRT20
KRT3
KRT6A
KRT6B
KRT75
LMO2
LNX1
MUC1
MXD3
MYO15B
NFX1
NUP153
NUP214
NUP54
NUP58
NUP88
NUP98
NUTF2
NXF1
NXF2
OGT
OIP5
OTUD6A
PBX2
PELI2
PHF21A
PIN1
PTMA
RANBP2
SMARCE1
SNAPC5
SP1
SSC5D
SUOX
THAP1
TLE4
TRAF3
TRIML2
TXLNA
TXN
USHBP1
WASHC3
XPO1
XPO6
38 interacting genes:
AKAP13
ARID4B
CALM1
CDCA8
CUL1
FHOD1
HDAC4
IFT140
IPO5
KPNA1
KPNA2
KPNB1
LRPAP1
MAP2K7
MDM2
MYBPC2
NFX1
NUP62
NXF1
OPN1LW
OPN1MW
PDLIM3
PRKN
PTEN
RAN
RANGAP1
SENP1
SP100
SUMO1
SUMO2
TAF1
TNPO1
TOP2B
UBE2I
UBTD1
WAS
XPO1
XPOT
Entrez ID
23636
5903
HPRD ID
05782
03111
Ensembl ID
ENSG00000213024
ENSG00000153201
Uniprot IDs
A0A024QZF1
P37198
P49792
PDB IDs
2H4D
5IJN
5IJO
1RRP
1XKE
1Z5S
2LAS
3UIN
3UIO
3UIP
4GA0
4I9Y
4L6E
4LQW
5CLL
5CLQ
Enriched GO Terms of Interacting Partners
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