MON1B and RABGEF1

Data Source:
BioGRID (pull down)

		MON1B	RABGEF1
Description		MON1 homolog B, secretory trafficking associated	RAB guanine nucleotide exchange factor 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mon1-Ccz1 Complex	Nucleolus Early Endosome Cytosol Early Endosome Membrane Recycling Endosome
	Molecular Function	Protein Binding	DNA Binding Guanyl-nucleotide Exchange Factor Activity Protein Binding Zinc Ion Binding Small GTPase Binding
	Biological Process	Protein Targeting To Vacuole Vesicle-mediated Transport Early Viral Transcription Late Viral Transcription	Protein Targeting To Membrane Endocytosis Regulation Of Catalytic Activity
Pathways		RAB GEFs exchange GTP for GDP on RABs	TBC/RABGAPs RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS		Antidepressant treatment resistance (> 2 drugs prescribed) ( 30700811) Immune response to measles-mumps-rubella vaccine ( 24811271) Metabolite levels ( 23823483) Multisite chronic pain ( 31194737) Number of sexual partners ( 30643258)	Aortic root size ( 21223598) Central corneal thickness ( 32528159 29760442)
Interacting Genes		6 interacting genes: RABGEF1 VPS11 VPS16 VPS18 VPS33A VPS41	50 interacting genes: ABI2 ANKRD29 AP1G1 ARRDC3 BLOC1S6 CCHCR1 CDC37 CIPC DAZAP2 DCTN2 DGCR6 DNAJC5 EMILIN1 GGA1 GGA2 GPRASP2 HOOK2 HRAS IHO1 KXD1 MID2 MON1A MON1B OIP5 RAB33B RAB4A RABEP1 RAD23A RASAL3 RNF11 RNF168 RPS27A SESTD1 SNAPIN SPART SSX3 TCHP TEAD4 THOC1 TRIM15 TRIM54 TXN2 UBA52 UBB UBC UBE2D1 UBE2D3 WASHC1 YWHAB ZC2HC1C
Entrez ID		22879	27342
HPRD ID		12342	11477
Ensembl ID		ENSG00000103111	ENSG00000154710
Uniprot IDs		B4DKA0 E7EW32 Q6ZR87 Q7L1V2	A0A024RDL6 A8K3R3 B3KMF1 Q9UJ41
PDB IDs			1TXU 2C7M 2C7N 2OT3 4N3X 4N3Y 4N3Z 4Q9U
Enriched GO Terms of Interacting Partners?
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