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FGF7 and PTX3
Data Source:
BioGRID
(pull down)
FGF7
PTX3
Description
fibroblast growth factor 7
pentraxin 3
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Extracellular Region
Extracellular Space
Cytoplasm
Golgi Apparatus
Extracellular Region
Extracellular Space
Extracellular Matrix
Specific Granule Lumen
Tertiary Granule Lumen
Molecular Function
Fibroblast Growth Factor Receptor Binding
Type 2 Fibroblast Growth Factor Receptor Binding
Protein Binding
Growth Factor Activity
Heparin Binding
Chemoattractant Activity
Complement Component C1q Complex Binding
(1->3)-beta-D-glucan Binding
Protein Binding
Identical Protein Binding
Virion Binding
Biological Process
MAPK Cascade
Positive Regulation Of Protein Phosphorylation
Signal Transduction
Positive Regulation Of Cell Population Proliferation
Fibroblast Growth Factor Receptor Signaling Pathway
Epidermis Development
Response To Wounding
Animal Organ Morphogenesis
Mesenchymal Cell Proliferation
Positive Regulation Of Gene Expression
Positive Regulation Of Keratinocyte Proliferation
Cell Differentiation
Lung Development
Regulation Of Cell Migration
Hair Follicle Morphogenesis
Actin Cytoskeleton Reorganization
Protein Localization To Cell Surface
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Epithelial Cell Proliferation
Positive Regulation Of Peptidyl-tyrosine Phosphorylation
Positive Chemotaxis
Positive Regulation Of Keratinocyte Migration
Positive Regulation Of Cell Division
Positive Regulation Of Protein Kinase B Signaling
Branching Involved In Salivary Gland Morphogenesis
Positive Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis
Regulation Of Branching Involved In Salivary Gland Morphogenesis By Mesenchymal-epithelial Signaling
Secretion By Lung Epithelial Cell Involved In Lung Growth
Ovarian Cumulus Expansion
Response To Yeast
Inflammatory Response
Opsonization
Extracellular Matrix Organization
Neutrophil Degranulation
Negative Regulation By Host Of Viral Process
Negative Regulation By Host Of Viral Exo-alpha-sialidase Activity
Negative Regulation By Host Of Viral Glycoprotein Metabolic Process
Innate Immune Response
Positive Regulation Of Nitric Oxide Biosynthetic Process
Negative Regulation Of Viral Entry Into Host Cell
Positive Regulation Of Phagocytosis
Negative Regulation Of Exo-alpha-sialidase Activity
Negative Regulation Of Glycoprotein Metabolic Process
Pathways
PI3K Cascade
PIP3 activates AKT signaling
FGFR2b ligand binding and activation
Activated point mutants of FGFR2
Constitutive Signaling by Aberrant PI3K in Cancer
Phospholipase C-mediated cascade; FGFR2
PI-3K cascade:FGFR2
SHC-mediated cascade:FGFR2
FRS-mediated FGFR2 signaling
Negative regulation of FGFR2 signaling
Signaling by FGFR2 in disease
RAF/MAP kinase cascade
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
Neutrophil degranulation
Drugs
Diseases
GWAS
Blood protein levels (
30072576
29875488
)
Lung adenocarcinoma (
28604730
)
Thyroid hormone levels (
23408906
)
Thyroid volume (
21565293
)
Body mass index (
26426971
)
Interacting Genes
14 interacting genes:
COL1A1
COL2A1
COL3A1
COL6A1
DESI1
DUSP3
FGFR1
FGFR2
FGFR3
FGFR4
HSPG2
NRP1
PTX3
UBQLN1
15 interacting genes:
C1QA
C1QB
C1QC
CFH
FGF1
FGF16
FGF17
FGF18
FGF2
FGF20
FGF22
FGF5
FGF7
FGF8
MTNR1A
Entrez ID
2252
5806
HPRD ID
01022
03928
Ensembl ID
ENSG00000140285
ENSG00000163661
Uniprot IDs
P21781
P26022
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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