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FGF7
Description
fibroblast growth factor 7
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Region
Extracellular Space
Cytoplasm
Golgi Apparatus
Molecular Function
Fibroblast Growth Factor Receptor Binding
Type 2 Fibroblast Growth Factor Receptor Binding
Protein Binding
Growth Factor Activity
Heparin Binding
Chemoattractant Activity
Biological Process
MAPK Cascade
Positive Regulation Of Protein Phosphorylation
Signal Transduction
Positive Regulation Of Cell Population Proliferation
Fibroblast Growth Factor Receptor Signaling Pathway
Epidermis Development
Response To Wounding
Animal Organ Morphogenesis
Mesenchymal Cell Proliferation
Positive Regulation Of Gene Expression
Positive Regulation Of Keratinocyte Proliferation
Cell Differentiation
Lung Development
Regulation Of Cell Migration
Hair Follicle Morphogenesis
Actin Cytoskeleton Reorganization
Protein Localization To Cell Surface
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Epithelial Cell Proliferation
Positive Regulation Of Peptidyl-tyrosine Phosphorylation
Positive Chemotaxis
Positive Regulation Of Keratinocyte Migration
Positive Regulation Of Cell Division
Positive Regulation Of Protein Kinase B Signaling
Branching Involved In Salivary Gland Morphogenesis
Positive Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis
Regulation Of Branching Involved In Salivary Gland Morphogenesis By Mesenchymal-epithelial Signaling
Secretion By Lung Epithelial Cell Involved In Lung Growth
Pathways
PI3K Cascade
PIP3 activates AKT signaling
FGFR2b ligand binding and activation
Activated point mutants of FGFR2
Constitutive Signaling by Aberrant PI3K in Cancer
Phospholipase C-mediated cascade; FGFR2
PI-3K cascade:FGFR2
SHC-mediated cascade:FGFR2
FRS-mediated FGFR2 signaling
Negative regulation of FGFR2 signaling
Signaling by FGFR2 in disease
RAF/MAP kinase cascade
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
Drugs
Diseases
GWAS
Blood protein levels (
30072576
29875488
)
Lung adenocarcinoma (
28604730
)
Thyroid hormone levels (
23408906
)
Thyroid volume (
21565293
)
Novel Interacting Genes
1 novel interacting genes:
PTEN
Interacting Genes
14 interacting genes:
COL1A1
COL2A1
COL3A1
COL6A1
DESI1
DUSP3
FGFR1
FGFR2
FGFR3
FGFR4
HSPG2
NRP1
PTX3
UBQLN1
Entrez ID
2252
HPRD ID
01022
Ensembl ID
ENSG00000140285
Uniprot IDs
P21781
PDB IDs
Enriched GO Terms of Interacting Partners
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