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ERCC3 and BLZF1
Data Source:
BioGRID
(two hybrid)
ERCC3
BLZF1
Description
ERCC excision repair 3, TFIIH core complex helicase subunit
basic leucine zipper nuclear factor 1
Image
No pdb structure
GO Annotations
Cellular Component
Nucleotide-excision Repair Factor 3 Complex
Transcription Factor TFIIH Core Complex
Nucleus
Nucleoplasm
Transcription Factor TFIID Complex
Transcription Factor TFIIH Holo Complex
Transcription Preinitiation Complex
Golgi Membrane
Nucleus
Nucleoplasm
Cytoplasm
Golgi Apparatus
Molecular Function
DNA Binding
Damaged DNA Binding
Helicase Activity
Protein Binding
ATP Binding
Protein C-terminus Binding
Transcription Factor Binding
ATPase Activity
3'-5' DNA Helicase Activity
Protein N-terminus Binding
Protein Binding
Enzyme Binding
Ubiquitin Protein Ligase Binding
Biological Process
Nucleotide-excision Repair, DNA Duplex Unwinding
DNA Topological Change
DNA Repair
Transcription-coupled Nucleotide-excision Repair
Nucleotide-excision Repair
Nucleotide-excision Repair, Preincision Complex Stabilization
Nucleotide-excision Repair, Preincision Complex Assembly
Nucleotide-excision Repair, DNA Incision, 3'-to Lesion
Nucleotide-excision Repair, DNA Incision, 5'-to Lesion
Transcription Initiation From RNA Polymerase I Promoter
Transcription Elongation From RNA Polymerase I Promoter
Termination Of RNA Polymerase I Transcription
Transcription By RNA Polymerase II
Transcription Initiation From RNA Polymerase II Promoter
Transcription Elongation From RNA Polymerase II Promoter
7-methylguanosine MRNA Capping
Apoptotic Process
Response To Oxidative Stress
Protein Localization
Response To UV
Viral Process
Nucleotide-excision Repair, DNA Incision
Hair Cell Differentiation
Positive Regulation Of Apoptotic Process
Embryonic Organ Development
Global Genome Nucleotide-excision Repair
Regulation Of Mitotic Cell Cycle Phase Transition
Golgi Organization
Golgi To Plasma Membrane Protein Transport
Pathways
Formation of RNA Pol II elongation complex
Formation of the Early Elongation Complex
Formation of HIV elongation complex in the absence of HIV Tat
Formation of the HIV-1 Early Elongation Complex
RNA Pol II CTD phosphorylation and interaction with CE during HIV infection
HIV Transcription Initiation
RNA Polymerase II HIV Promoter Escape
Transcription of the HIV genome
Formation of HIV-1 elongation complex containing HIV-1 Tat
Tat-mediated elongation of the HIV-1 transcript
NoRC negatively regulates rRNA expression
Formation of Incision Complex in GG-NER
Dual Incision in GG-NER
RNA Polymerase II Pre-transcription Events
Formation of TC-NER Pre-Incision Complex
Transcription-Coupled Nucleotide Excision Repair (TC-NER)
Dual incision in TC-NER
Gap-filling DNA repair synthesis and ligation in TC-NER
TP53 Regulates Transcription of DNA Repair Genes
mRNA Capping
RNA Polymerase I Transcription Initiation
RNA Polymerase I Promoter Escape
RNA Polymerase II Promoter Escape
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
RNA Polymerase I Transcription Termination
RNA Polymerase II Transcription Initiation
RNA Polymerase II Transcription Elongation
RNA Polymerase II Transcription Initiation And Promoter Clearance
RNA Pol II CTD phosphorylation and interaction with CE
Golgi Cisternae Pericentriolar Stack Reorganization
Drugs
Diseases
Disorders of nucleotide excision repair, including: Xeroderma pigmentosum (XP); Cockayne syndrome (CS); UV-sensitive syndrome (UVS); Trichothiodystrophy (TTD); Cerebro-oculo-facio-skeletal syndrome (COFS); XFE progeroid syndrome
GWAS
Interacting Genes
37 interacting genes:
ADAMTSL4
AR
BCR
BLZF1
CCNC
CCNH
CDC42
CDK7
CDK8
CEP70
CEP76
E2F1
ERCC2
GOLGA2
GTF2E1
GTF2E2
GTF2H1
GTF2H2
GTF2H3
GTF2H4
GTF2H5
KPNA3
MAGED1
MCF2
MNAT1
MSANTD2
PSMC5
RAD52
ROPN1
SNW1
SRPK2
TP53
TRIM14
TRIM27
XIAP
XPC
ZSCAN1
101 interacting genes:
AKAP9
AMOTL2
ANKS1A
AQP1
BAG4
BANP
BCL6
BEX2
CARD9
CCDC120
CCDC33
CCNH
CDC37
CDK18
CFAP206
CHCHD3
CINP
CKS2
CTNNA3
DNMT3L
ENKD1
ERCC3
EWSR1
EXOC8
FAM124B
FAM90A1
FBF1
FHL2
FRMD6
FRS3
GEM
GORASP2
HCLS1
HDAC4
HOXA1
HOXC8
IGFN1
IKZF3
IL16
IQUB
KANK2
KAT5
KCTD9
KDM1A
KIF9
KLHL38
LGALS14
LMO1
LMO2
LMO3
LNX1
MID2
MISP
MKRN3
NTAQ1
OAZ3
PCDHB12
PIK3R3
PKN1
POLR1C
PRKAB2
PRMT6
PRPF18
PSMA1
PTPN11
RAB2A
RAB2B
RAB39A
RANBP3
RHOJ
SCNM1
SMAD3
SMARCB1
SPRED1
SRA1
SSX2
SUV39H2
SYT17
TBC1D22B
TBC1D7
TCAP
TCF19
TEKT4
TNS2
TRAPPC2L
TRIM59
TSC22D4
TSTD2
TTC23
TXNDC5
USHBP1
VPS28
ZBTB16
ZBTB24
ZGPAT
ZMAT1
ZNF124
ZNF410
ZNF688
ZNF76
ZZZ3
Entrez ID
2071
8548
HPRD ID
00593
16367
Ensembl ID
ENSG00000163161
ENSG00000117475
Uniprot IDs
B3KRG2
B3KTH1
G3V1S1
P19447
Q9H2G9
PDB IDs
4ERN
5IVW
5IY6
5IY7
5IY8
5IY9
5OF4
6NMI
6O9L
6O9M
6RO4
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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