SUSD3 and BCL2L2

Data Source:
BioGRID (two hybrid)

		SUSD3	BCL2L2
Description		sushi domain containing 3	BCL2 like 2
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane	Mitochondrial Outer Membrane Bcl-2 Family Protein Complex
	Molecular Function	Protein Binding	Protein Binding Identical Protein Binding Protein Homodimerization Activity Protein Heterodimerization Activity Disordered Domain Specific Binding
	Biological Process		Spermatogenesis Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Negative Regulation Of Apoptotic Process Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Negative Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways
Drugs			Navitoclax
Diseases
GWAS		Plateletcrit ( 32888494)	Height ( 28552196)
Interacting Genes		27 interacting genes: ANKRD46 APP ASGR1 ATP6V0C BCL2L2 CGRRF1 CLDN19 CLDN23 CLEC7A CNIH3 CXCL9 EDDM3B HHATL KTN1 OLFM4 PLP1 RPRM SEC22A SMAGP SMCO4 TMED8 TMEM11 TMEM147 TMEM182 TMEM47 TMEM98 TMPRSS4	53 interacting genes: ANKS6 APOC1 APOC2 APOC4 ATP5PF BAD BAK1 BAX BBC3 BCL2L11 BHLHA9 BID BIK BMF BNIP3 BNIP5 C10orf67 CD79A CHODL CIDEB CISD2 CLDN7 ERVFRD-1 FATE1 G0S2 GORAB GPR151 GPX8 HRK KASH5 KCNJ6 LMNA LRRIQ1 MGST2 MUC1 PANX1 PPP1CA PSCA RHBDD2 S100B SAR1A SGPL1 SLC35C2 SLC35E3 SLC39A2 SLC39A6 STOM SUSD3 TCF4 TEX11 TMEM139 TMX1 TP53
Entrez ID		203328	599
HPRD ID		15453	03569
Ensembl ID		ENSG00000157303	ENSG00000129473
Uniprot IDs		A0A087WVN2 Q96L08	Q92843
PDB IDs			1MK3 1O0L 1ZY3 2Y6W 4CIM
Enriched GO Terms of Interacting Partners?
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