DTX3 and TRIP10

Data Source:
BioGRID (two hybrid)

		DTX3	TRIP10
Description		deltex E3 ubiquitin ligase 3	thyroid hormone receptor interactor 10
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm	Phagocytic Cup Nucleoplasm Cytoplasm Lysosome Golgi Apparatus Cytosol Cytoskeleton Cell Cortex Cell Projection Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function	Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity	Protein Binding Lipid Binding Identical Protein Binding
	Biological Process	Notch Signaling Pathway Protein Ubiquitination	Endocytosis Cell Communication Signal Transduction Actin Cytoskeleton Organization Regulation Of Small GTPase Mediated Signal Transduction Membrane Organization
Pathways			Rho GTPase cycle Clathrin-mediated endocytosis
Drugs
Diseases
GWAS
Interacting Genes		44 interacting genes: ARF5 BAG3 DTX1 DTX2 EPM2AIP1 FAM90A1 FYN GRB2 MAPK9 NCK2 NFKBID NOTCH2 OSTF1 PARP11 PTK6 RNF141 RNF38 TCEANC TRAF4 TRIP10 UBASH3A UBASH3B UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2DNL UBE2E1 UBE2E2 UBE2E3 UBE2H UBE2K UBE2L3 UBE2L6 UBE2V1 UBE2W UEVLD USP1 USP2 USP21 XIAP YES1 ZDHHC17 ZMYND19	41 interacting genes: ABI1 ABL2 AKAP9 ARHGAP12 ARHGAP17 CDC42 CREBBP CTNNB1 DNM2 DTX3 HOXC11 HTT JRK LYN MEOX1 MEOX2 NKX2-5 PAX6 PDE6G POT1 PRKACA RHOJ RHOQ RIN1 RXRA SF3A2 SH3BP1 SMARCE1 SMURF1 SRC STAT3 TERF1 THAP1 THRB TINF2 UTF1 WAS WASF1 WASL WBP11 ZBTB7B
Entrez ID		196403	9322
HPRD ID		16842	05142
Ensembl ID		ENSG00000178498	ENSG00000125733
Uniprot IDs		A0A024RB96 Q8N9I9	Q15642 W4VSQ9
PDB IDs			2CT4 2EFK 2KE4
Enriched GO Terms of Interacting Partners?
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