DTX3 and RNF141

		DTX3	RNF141
Description		deltex E3 ubiquitin ligase 3	ring finger protein 141
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm	Membrane
	Molecular Function	Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity	Ubiquitin-protein Transferase Activity Protein Binding Metal Ion Binding
	Biological Process	Notch Signaling Pathway Protein Ubiquitination	Regulation Of Transcription, DNA-templated Protein Autoubiquitination
Pathways
Drugs
Diseases
GWAS			Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892)
Interacting Genes		44 interacting genes: ARF5 BAG3 DTX1 DTX2 EPM2AIP1 FAM90A1 FYN GRB2 MAPK9 NCK2 NFKBID NOTCH2 OSTF1 PARP11 PTK6 RNF141 RNF38 TCEANC TRAF4 TRIP10 UBASH3A UBASH3B UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2DNL UBE2E1 UBE2E2 UBE2E3 UBE2H UBE2K UBE2L3 UBE2L6 UBE2V1 UBE2W UEVLD USP1 USP2 USP21 XIAP YES1 ZDHHC17 ZMYND19	7 interacting genes: DTX3 MAP3K1 MVK PLK3 SMURF1 TRIM24 TRIM8
Entrez ID		196403	50862
HPRD ID		16842	11509
Ensembl ID		ENSG00000178498	ENSG00000110315
Uniprot IDs		A0A024RB96 Q8N9I9	Q8WVD5
PDB IDs			2ECN 5XEK
Enriched GO Terms of Interacting Partners?
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