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RNF40 and UBE2B
Data Source:
BioGRID
(pull down)
RNF40
UBE2B
Description
ring finger protein 40
ubiquitin conjugating enzyme E2 B
Image
No pdb structure
GO Annotations
Cellular Component
Ubiquitin Ligase Complex
Nucleus
Nucleoplasm
Cytosol
Membrane
Extrinsic Component Of Membrane
HULC Complex
Neuron Projection
Axon Terminus
Chromatin
XY Body
Nucleus
Nucleoplasm
Replication Fork
Cytoplasm
Plasma Membrane
HULC Complex
Molecular Function
MRNA 3'-UTR Binding
Ubiquitin-protein Transferase Activity
Protein Binding
Syntaxin-1 Binding
Ubiquitin Conjugating Enzyme Binding
Ubiquitin Protein Ligase Binding
Protein Homodimerization Activity
Protein-containing Complex Binding
Metal Ion Binding
Ubiquitin-protein Transferase Activity
Protein Binding
ATP Binding
Ubiquitin Protein Ligase Binding
Ubiquitin Conjugating Enzyme Activity
Biological Process
Ubiquitin-dependent Protein Catabolic Process
Regulation Of Mitotic Cell Cycle
Histone Monoubiquitination
Protein Ubiquitination
Histone H2B Ubiquitination
Response To Peptide Hormone
Negative Regulation Of MRNA Polyadenylation
Positive Regulation Of Proteasomal Protein Catabolic Process
Positive Regulation Of Protein Polyubiquitination
Positive Regulation Of Histone H2B Ubiquitination
Protein Polyubiquitination
In Utero Embryonic Development
DNA Repair
Postreplication Repair
Ubiquitin-dependent Protein Catabolic Process
Protein Monoubiquitination
Cellular Response To DNA Damage Stimulus
Spermatogenesis
Sperm Axoneme Assembly
Response To UV
Positive Regulation Of Reciprocal Meiotic Recombination
Protein Ubiquitination
Histone Ubiquitination
Negative Regulation Of Histone Phosphorylation
Histone H2A Ubiquitination
Response To Drug
DNA Damage Response, Detection Of DNA Damage
Negative Regulation Of Apoptotic Process
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Negative Regulation Of CAMP-mediated Signaling
Meiotic Telomere Clustering
Protein Stabilization
Chiasma Assembly
Protein Autoubiquitination
Histone Lysine Demethylation
Synaptonemal Complex Organization
Protein K63-linked Ubiquitination
Heterochromatin Maintenance
Protein K48-linked Ubiquitination
Protein K11-linked Ubiquitination
Positive Regulation Of Canonical Wnt Signaling Pathway
Pathways
E3 ubiquitin ligases ubiquitinate target proteins
Recognition of DNA damage by PCNA-containing replication complex
Synthesis of active ubiquitin: roles of E1 and E2 enzymes
E3 ubiquitin ligases ubiquitinate target proteins
Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS
Immunoglobulin light chain (AL) amyloidosis (
28025584
)
Relative amplitude of rest-activity cycles (
30120083
)
Interacting Genes
26 interacting genes:
AMOTL2
ATM
CCDC146
CDC73
DISC1
DUSP29
EEF1D
ITSN1
KIF11
MEOX2
MSL1
MTNR1B
NCBP1
NINL
RB1
RNF20
SFR1
TRIM51
UBE2A
UBE2B
UBE2D2
UBE2E1
UBE2I
UBE2L6
ZCCHC12
ZNF451
25 interacting genes:
BIRC2
CBX5
CDKN1B
CNOT4
CRMP1
CTNNB1
H2AC20
HERPUD2
MED31
PCNA
PRKN
RAD18
RC3H1
RC3H2
RNF20
RNF4
RNF40
TRIM14
TRIM45
UBA1
UBR1
UBR2
UBR3
UBR5
UNC119
Entrez ID
9810
7320
HPRD ID
07411
01533
Ensembl ID
ENSG00000103549
ENSG00000119048
Uniprot IDs
A8K6K1
O75150
P63146
PDB IDs
1JAS
1NXA
2Y4W
2YB6
2YBF
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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