RNF32 and PRDX2

Data Source:
BioGRID (two hybrid)

		RNF32	PRDX2
Description		ring finger protein 32	peroxiredoxin 2
Image		No pdb structure
GO Annotations	Cellular Component	Endosome Cytosol Aggresome Nuclear Body	Cytoplasm Cytosol Extracellular Exosome
	Molecular Function	Protein Binding Metal Ion Binding	Protein Binding Thioredoxin Peroxidase Activity Antioxidant Activity
	Biological Process		Activation Of MAPK Activity Respiratory Burst Involved In Inflammatory Response Response To Oxidative Stress Regulation Of Hydrogen Peroxide Metabolic Process Removal Of Superoxide Radicals Positive Regulation Of Blood Coagulation Negative Regulation Of Lipopolysaccharide-mediated Signaling Pathway Negative Regulation Of NF-kappaB Transcription Factor Activity Response To Lipopolysaccharide Cellular Response To Stress Cellular Response To Oxidative Stress T Cell Proliferation Hydrogen Peroxide Catabolic Process Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Leukocyte Activation Cell Redox Homeostasis Negative Regulation Of T Cell Differentiation Thymus Development Homeostasis Of Number Of Cells Negative Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Pathways			Detoxification of Reactive Oxygen Species TP53 Regulates Metabolic Genes Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models
Drugs			3-sulfino-L-alanine N-Carbamoyl-Alanine Copper
Diseases
GWAS		Glomerular filtration rate (creatinine) ( 26831199)	Platelet distribution width ( 32888494)
Interacting Genes		42 interacting genes: A2M APOE APP BLMH CDC37 CDK5 CEP55 CYP2C8 CYP2C9 ECSIT ELAVL3 EXOC6 EXOSC1 FARSA FBXL12 FBXW4 FIBP GCDH HOXC4 IFIT3 IFIT5 LONP1 LOXL4 LZTS2 MAST1 MKRN3 MNAT1 NOS3 OGA PAXIP1 PRAM1 PRDX2 PSEN1 PSEN2 RAB3A RAB3D RAD23A RPP30 STAMBPL1 TRIM23 TRIM74 UBE2K	24 interacting genes: A2M APOE APP BAD CA4 CD320 CDC37 COPS5 ECSIT EXOC6 IFIT5 MAST1 NLGN3 PDGFRB PPP2R1A PPP2R1B PRDX4 PSEN1 RNF32 SAT1 SUMO4 TXNDC5 UTY YWHAZ
Entrez ID		140545	7001
HPRD ID		11517	02763
Ensembl ID		ENSG00000105982	ENSG00000167815
Uniprot IDs		A0A024RD87 G5E940 Q9H0A6	P32119 V9HW12
PDB IDs			1QMV 5B8A 5B8B 5IJT
Enriched GO Terms of Interacting Partners?
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