PRDX2 and RNF32

Data Source:
BioGRID (two hybrid)

		PRDX2	RNF32
Description		peroxiredoxin 2	ring finger protein 32
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Extracellular Exosome	Endosome Cytosol Aggresome Nuclear Body
	Molecular Function	Protein Binding Thioredoxin Peroxidase Activity Antioxidant Activity	Protein Binding Metal Ion Binding
	Biological Process	Activation Of MAPK Activity Respiratory Burst Involved In Inflammatory Response Response To Oxidative Stress Regulation Of Hydrogen Peroxide Metabolic Process Removal Of Superoxide Radicals Positive Regulation Of Blood Coagulation Negative Regulation Of Lipopolysaccharide-mediated Signaling Pathway Negative Regulation Of NF-kappaB Transcription Factor Activity Response To Lipopolysaccharide Cellular Response To Stress Cellular Response To Oxidative Stress T Cell Proliferation Hydrogen Peroxide Catabolic Process Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Leukocyte Activation Cell Redox Homeostasis Negative Regulation Of T Cell Differentiation Thymus Development Homeostasis Of Number Of Cells Negative Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Pathways		Detoxification of Reactive Oxygen Species TP53 Regulates Metabolic Genes Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models
Drugs		3-sulfino-L-alanine N-Carbamoyl-Alanine Copper
Diseases
GWAS		Platelet distribution width ( 32888494)	Glomerular filtration rate (creatinine) ( 26831199)
Interacting Genes		24 interacting genes: A2M APOE APP BAD CA4 CD320 CDC37 COPS5 ECSIT EXOC6 IFIT5 MAST1 NLGN3 PDGFRB PPP2R1A PPP2R1B PRDX4 PSEN1 RNF32 SAT1 SUMO4 TXNDC5 UTY YWHAZ	42 interacting genes: A2M APOE APP BLMH CDC37 CDK5 CEP55 CYP2C8 CYP2C9 ECSIT ELAVL3 EXOC6 EXOSC1 FARSA FBXL12 FBXW4 FIBP GCDH HOXC4 IFIT3 IFIT5 LONP1 LOXL4 LZTS2 MAST1 MKRN3 MNAT1 NOS3 OGA PAXIP1 PRAM1 PRDX2 PSEN1 PSEN2 RAB3A RAB3D RAD23A RPP30 STAMBPL1 TRIM23 TRIM74 UBE2K
Entrez ID		7001	140545
HPRD ID		02763	11517
Ensembl ID		ENSG00000167815	ENSG00000105982
Uniprot IDs		P32119 V9HW12	A0A024RD87 G5E940 Q9H0A6
PDB IDs		1QMV 5B8A 5B8B 5IJT
Enriched GO Terms of Interacting Partners?
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