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CRH and KRTAP10-8
Data Source:
BioGRID
(two hybrid)
CRH
KRTAP10-8
Description
corticotropin releasing hormone
keratin associated protein 10-8
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Region
Extracellular Space
Cytoplasm
Varicosity
Perikaryon
Synapse
Cytosol
Keratin Filament
Molecular Function
Signaling Receptor Binding
Hormone Activity
Neuropeptide Hormone Activity
Protein Binding
Corticotropin-releasing Hormone Activity
Corticotropin-releasing Hormone Receptor 1 Binding
Corticotropin-releasing Hormone Receptor 2 Binding
Protein Binding
Identical Protein Binding
Biological Process
Positive Regulation Of Protein Phosphorylation
Synaptic Transmission, Dopaminergic
Negative Regulation Of Systemic Arterial Blood Pressure
Inflammatory Response
Signal Transduction
G Protein-coupled Receptor Signaling Pathway
Chemical Synaptic Transmission
Female Pregnancy
Parturition
Learning Or Memory
Steroid Metabolic Process
Positive Regulation Of Cell Population Proliferation
Associative Learning
Hormone-mediated Apoptotic Signaling Pathway
Positive Regulation Of Gene Expression
Negative Regulation Of Gene Expression
Negative Regulation Of Norepinephrine Secretion
Positive Regulation Of Circadian Sleep/wake Cycle, Wakefulness
Positive Regulation Of Cell Death
Regulation Of Serotonin Secretion
Diterpenoid Metabolic Process
Hypothalamus Development
Negative Regulation Of Epinephrine Secretion
Negative Regulation Of Luteinizing Hormone Secretion
Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus
Response To Immobilization Stress
Negative Regulation Of Circadian Sleep/wake Cycle, REM Sleep
Response To Drug
Response To Estrogen
Positive Regulation Of CAMP-mediated Signaling
Response To Ethanol
Response To Ether
Response To Pain
Ion Homeostasis
Response To Corticosterone
Positive Regulation Of Corticotropin Secretion
Positive Regulation Of Cortisol Secretion
Long-term Synaptic Potentiation
Positive Regulation Of Digestive System Process
Negative Regulation Of Cell Death
Negative Regulation Of Glucagon Secretion
Cellular Response To Cocaine
Cellular Response To Dexamethasone Stimulus
Positive Regulation Of Calcium Ion Import
Regulation Of NMDA Receptor Activity
Positive Regulation Of Corticosterone Secretion
Positive Regulation Of Behavioral Fear Response
Keratinization
Pathways
Class B/2 (Secretin family receptors)
G alpha (s) signalling events
MECP2 regulates transcription of neuronal ligands
ADORA2B mediated anti-inflammatory cytokines production
Keratinization
Drugs
Corticotropin
D-Phenylalanine
2-aminoisobutyric acid
Diseases
GWAS
Adult body size (
32376654
)
Coronary heart disease event reduction (statin therapy interaction) (
22666496
)
Interacting Genes
12 interacting genes:
CRHR1
CRHR2
CYSRT1
KRT31
KRTAP1-3
KRTAP1-5
KRTAP10-8
KRTAP5-9
KRTAP9-3
MDFI
NBPF19
NOTCH2NLA
388 interacting genes:
-
ACY3
ADAM12
ADAMTS1
ADAMTSL3
ADAMTSL4
AEBP2
AEN
AK3
ALDH3B1
ALPI
ALPP
AMMECR1
ANKS1A
AP1M1
APOL6
AQP1
AREG
ARID5A
ASPSCR1
ATG9A
ATP5F1D
AVPI1
AXIN2
BAHD1
BCL6B
BEX2
BMP7
BRME1
C10orf62
C11orf87
C17orf50
C19orf25
C22orf39
C2orf68
C3
CAMK1G
CARD10
CARHSP1
CATSPER1
CCDC26
CCNJL
CHIC2
CHRD
CHRNG
CLK4
CNNM3
COL8A1
COX17
CRCT1
CREB5
CRH
CRY2
CSF1
CTRC
CYP2S1
CYSRT1
DAAM2
DCX
DDX43
DDX55
DDX6
DERL2
DHRS1
DHX57
DMRT3
DOCK2
ECE1
EFEMP2
EIF4E2
ENKD1
EPDR1
FADS6
FAH
FAM110A
FAM161A
FAM221B
FAM27E3
FAM71C
FAM74A4
FAM76B
FAM90A1
FARS2
FBXO34
FBXW5
FEZF1
FOXB1
FRS3
FTHL17
FZD10
GEM
GFOD1
GLIDR
GLP1R
GLRX3
GLYAT
GNAI2
GNE
GOLGA8EP
GPANK1
GPHB5
GPRIN2
GRN
GUCD1
HAPLN2
HCK
HHEX
HOXA1
HOXB5
HOXB9
HOXC8
HPCAL1
HS6ST1
HSD3B7
HSPA12B
HSPD1
ICAM1
IGFBP6
IGSF8
IL10
IL16
IL2RG
INO80B
INTS5
IP6K3
ITGB2
ITGB4
ITGB5
JOSD1
JPH3
KLHL38
KLK8
KPRP
KRT20
KRT83
KRTAP1-1
KRTAP1-3
KRTAP10-1
KRTAP10-10
KRTAP10-11
KRTAP10-3
KRTAP10-5
KRTAP10-7
KRTAP10-9
KRTAP11-1
KRTAP12-1
KRTAP12-2
KRTAP12-3
KRTAP15-1
KRTAP17-1
KRTAP19-7
KRTAP3-1
KRTAP3-2
KRTAP4-11
KRTAP4-12
KRTAP4-2
KRTAP4-4
KRTAP4-5
KRTAP4-7
KRTAP5-11
KRTAP5-2
KRTAP5-3
KRTAP5-4
KRTAP5-6
KRTAP5-9
KRTAP9-2
KRTAP9-3
KRTAP9-4
KRTAP9-8
LAGE3
LASP1
LCE1A
LCE1B
LCE1C
LCE1D
LCE1E
LCE1F
LCE2A
LCE2B
LCE2C
LCE2D
LCE3A
LCE3B
LCE3C
LCE3D
LCE3E
LCE4A
LCE5A
LELP1
LENG1
LINC00656
LMF2
LNX1
LRCH4
LRFN4
LUZP4
LYVE1
MACROH2A1
MAPKBP1
MATN3
MEIS2
MELTF
MEOX2
MLLT6
MOBP
MTA1
MUL1
MXI1
MYPOP
NAB2
NAXD
NBPF19
NECTIN2
NECTIN3
NEK6
NKD1
NOTCH2NLA
NPDC1
NR1D2
NR4A3
NTN4
NUFIP2
OLIG3
OPCML
OTX1
P2RX7
P2RY6
PAX5
PCED1A
PCSK5
PDE9A
PDIA4
PGAP6
PGLS
PHLDA1
PIGS
PIN1
PKD2
PLSCR4
POM121L8P
POU1F1
POU4F2
PRKAB2
PRPF31
PRR13
PRR19
PTGER3
PTK7
PTPMT1
PTPRH
PVR
QPRT
R3HDM2
RAB19
RAB3A
RALGDS
RANBP3
RASD1
RECK
RGL2
RHBDL1
RHNO1
RNF38
RNF8
RPS19BP1
RPS28
RTN4RL1
SCARF1
SCNM1
SEMA3B
SH3GLB2
SHFL
SLC13A5
SLC22A23
SLC23A1
SLC25A10
SLC25A31
SLC25A42
SLC6A20
SLIT1
SMARCE1
SMCP
SMG9
SMOC1
SPACA9
SPAG8
SPATA24
SPATA3
SPRY1
SPRY2
SSC4D
STK16
SUSD2
SUSD6
SUV39H1
TACSTD2
TAPBPL
TBC1D16
TBC1D23
TCAF1
TCEA2
TCEANC
TFAP2D
TGFB1
THAP10
THAP7
TIE1
TLE5
TMEM140
TMEM150A
TMIE
TNIP3
TNP2
TNPO3
TNS2
TRIM41
TRIM42
TRPV6
TSPAN4
TTC23
TXNDC5
TYMSOS
TYRO3
UBL5
UTP23
UXT
VASN
VENTX
VEZF1
VGLL3
VPS11
VWC2
VWC2L
WIF1
WNT11
WT1
WT1-AS
YIPF3
YY1
ZBTB24
ZBTB25
ZDHHC1
ZFYVE21
ZIC1
ZNF101
ZNF107
ZNF121
ZNF124
ZNF138
ZNF165
ZNF20
ZNF23
ZNF250
ZNF264
ZNF266
ZNF319
ZNF32
ZNF330
ZNF408
ZNF414
ZNF417
ZNF439
ZNF440
ZNF444
ZNF473
ZNF490
ZNF491
ZNF497
ZNF524
ZNF559
ZNF572
ZNF575
ZNF578
ZNF580
ZNF581
ZNF587
ZNF625
ZNF648
ZNF669
ZNF696
ZNF697
ZNF775
ZNF786
ZNF79
ZNF792
ZNF837
ZSCAN12
ZSCAN21
Entrez ID
1392
386681
HPRD ID
07172
11194
Ensembl ID
ENSG00000147571
ENSG00000187766
Uniprot IDs
A0A0S2Z478
P06850
P60410
PDB IDs
1GO9
1GOE
3EHT
3EHU
6P9X
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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