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CREBBP and H3C1
Data Source:
BioGRID
(enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, pull down, enzymatic study)
CREBBP
H3C1
Description
CREB binding protein
H3 clustered histone 1
Image
GO Annotations
Cellular Component
Histone Acetyltransferase Complex
Chromatin
Nucleus
Nucleoplasm
Transcription Regulator Complex
Cytoplasm
Nuclear Body
Nuclear Chromosome
Nucleosome
Extracellular Region
Nucleus
Nucleoplasm
Membrane
Protein-containing Complex
Extracellular Exosome
Molecular Function
RNA Polymerase II Transcription Factor Binding
RNA Polymerase II Activating Transcription Factor Binding
P53 Binding
Chromatin Binding
Damaged DNA Binding
Transcription Coactivator Activity
Transcription Corepressor Activity
Histone Acetyltransferase Activity
Protein Binding
Transcription Factor Binding
Zinc Ion Binding
Acetyltransferase Activity
Chromatin DNA Binding
MRF Binding
Peptide-lysine-N-acetyltransferase Activity
DNA Binding
Protein Binding
Cadherin Binding
Protein Heterodimerization Activity
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Response To Hypoxia
Stimulatory C-type Lectin Receptor Signaling Pathway
Regulation Of Transcription, DNA-templated
Transcription Initiation From RNA Polymerase II Promoter
Protein Acetylation
Signal Transduction
Notch Signaling Pathway
Positive Regulation Of Transcription Of Notch Receptor Target
Regulation Of Smoothened Signaling Pathway
Viral Process
Histone Acetylation
N-terminal Peptidyl-lysine Acetylation
Protein Phosphopantetheinylation
Regulation Of Lipid Metabolic Process
Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Protein Destabilization
Positive Regulation Of Type I Interferon Production
Cellular Response To UV
Homeostatic Process
Embryonic Digit Morphogenesis
Regulation Of Apoptotic Process
Regulation Of Myeloid Cell Differentiation
Positive Regulation Of Notch Signaling Pathway
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription By RNA Polymerase II
Rhythmic Process
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia
Protein-containing Complex Assembly
Regulation Of Cellular Response To Heat
Beta-catenin-TCF Complex Assembly
Histone Glutamine Methylation
RDNA Heterochromatin Assembly
Chromatin Organization
Nucleosome Assembly
DNA Replication-dependent Nucleosome Assembly
Blood Coagulation
Telomere Organization
Interleukin-7-mediated Signaling Pathway
Cellular Protein Metabolic Process
Regulation Of Megakaryocyte Differentiation
Negative Regulation Of Gene Expression, Epigenetic
Regulation Of Gene Silencing By MiRNA
Regulation Of Gene Silencing
Pathways
Regulation of gene expression by Hypoxia-inducible Factor
RORA activates gene expression
BMAL1:CLOCK,NPAS2 activates circadian gene expression
Pre-NOTCH Transcription and Translation
Pre-NOTCH Transcription and Translation
PPARA activates gene expression
PPARA activates gene expression
Formation of the beta-catenin:TCF transactivating complex
Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells
NOTCH1 Intracellular Domain Regulates Transcription
NOTCH1 Intracellular Domain Regulates Transcription
Transcriptional activation of mitochondrial biogenesis
Activation of gene expression by SREBF (SREBP)
Constitutive Signaling by NOTCH1 PEST Domain Mutants
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants
LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production
HATs acetylate histones
Attenuation phase
Notch-HLH transcription pathway
Transcriptional regulation of white adipocyte differentiation
Transcriptional regulation of white adipocyte differentiation
SUMOylation of transcription cofactors
Regulation of lipid metabolism by PPARalpha
Circadian Clock
Activation of anterior HOX genes in hindbrain development during early embryogenesis
CD209 (DC-SIGN) signaling
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release
Activation of the TFAP2 (AP-2) family of transcription factors
RUNX1 regulates transcription of genes involved in differentiation of myeloid cells
RUNX3 regulates NOTCH signaling
RUNX3 regulates NOTCH signaling
NOTCH3 Intracellular Domain Regulates Transcription
NOTCH3 Intracellular Domain Regulates Transcription
NOTCH4 Intracellular Domain Regulates Transcription
Estrogen-dependent gene expression
TRAF3-dependent IRF activation pathway
TRAF6 mediated IRF7 activation
FOXO-mediated transcription of cell death genes
Regulation of FOXO transcriptional activity by acetylation
Regulation of FOXO transcriptional activity by acetylation
Interleukin-7 signaling
Interleukin-7 signaling
Pre-NOTCH Transcription and Translation
Formation of the beta-catenin:TCF transactivating complex
PRC2 methylates histones and DNA
Condensation of Prophase Chromosomes
Oxidative Stress Induced Senescence
Senescence-Associated Secretory Phenotype (SASP)
HDACs deacetylate histones
PKMTs methylate histone lysines
HDMs demethylate histones
HATs acetylate histones
HATs acetylate histones
RMTs methylate histone arginines
Chromatin modifying enzymes
SIRT1 negatively regulates rRNA expression
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression
NoRC negatively regulates rRNA expression
NoRC negatively regulates rRNA expression
B-WICH complex positively regulates rRNA expression
DNA methylation
Transcriptional regulation by small RNAs
Activation of anterior HOX genes in hindbrain development during early embryogenesis
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3
RNA Polymerase I Promoter Opening
RNA Polymerase I Promoter Escape
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
RUNX1 regulates transcription of genes involved in differentiation of HSCs
Estrogen-dependent gene expression
Meiotic recombination
HCMV Early Events
HCMV Late Events
Transcriptional regulation of granulopoiesis
Amyloid fiber formation
Factors involved in megakaryocyte development and platelet production
Drugs
9-ACETYL-2,3,4,9-TETRAHYDRO-1H-CARBAZOL-1-ONE
Diseases
Rubinstein-Taybi syndrome
GWAS
Gut microbiota (bacterial taxa, hurdle binary method) (
32572223
)
Heel bone mineral density (
30598549
)
Metabolite levels (HVA/5-HIAA ratio) (
23319000
)
Neutrophil count (
32888494
)
Nonsyndromic cleft lip with cleft palate (
28232668
)
Nonsyndromic cleft lip with or without cleft palate (
25775280
)
Obesity-related traits (
23251661
)
Pre-treatment viral load in HIV-1 infection (
31219150
)
QT interval (
24952745
)
QT interval (drug interaction) (
23459443
)
White blood cell count (
32888494
)
Interacting Genes
295 interacting genes:
ACTA2
ACVR1
AFP
AIRE
AKT1
ALX1
ANAPC5
ANAPC7
AP1B1
APC
AR
ATF1
ATF3
ATF4
ATF7IP
ATRX
BCL3
BCL6
BRCA1
BRIP1
CALCOCO1
CAMK4
CARM1
CASP8AP2
CBX4
CDC25B
CDH2
CDK5RAP3
CDX2
CEBPA
CEBPB
CEBPD
CENPJ
CHAF1A
CHD3
CHUK
CITED1
CITED2
CNOT3
CPSF4
CREB1
CREM
CRX
CSK
CSNK2A1
CSNK2A2
CTBP1
CTNNB1
CUX1
DACH1
DAXX
DDX17
DDX5
DEK
DYRK1A
E2F1
E2F3
E2F5
EBF1
EGR1
EID1
EID3
EIF2B1
EIF3D
ELF3
ELK1
EP300
ESR1
ETS1
ETS2
EWSR1
FAF1
FBXL19
FBXO38
FGFR1
FHL2
FOS
FOXM1
FOXO1
FOXO4
GABPA
GAK
GATA1
GATAD2A
GCM1
GLI3
GMEB1
GMEB2
GTF2B
H2BC21
H2BC3
H3-3A
H3-4
H3C1
H4-16
H4C1
HBP1
HCK
HDAC1
HDAC3
HIF1A
HIPK1
HIPK2
HIPK3
HLF
HMGA1
HMGB1
HMGB2
HMGXB4
HNF1A
HNF1B
HNF4A
HOXA10
HOXA11
HOXA9
HOXB1
HOXB2
HOXB3
HOXB4
HOXB6
HOXB7
HOXB9
HOXD10
HOXD12
HOXD13
HOXD4
HSF1
HTT
IKBKG
IRF1
IRF3
IRF5
IRF7
JDP2
JUN
KAT2A
KAT2B
KAT5
KAT6A
KDM3B
KHDRBS1
KISS1
KLF1
KLF13
KLF4
KLF5
KMT2A
KPNA2
KPNA6
LDLR
LIG4
LYN
MAF
MAFG
MAML1
MAML2
MAP3K5
MAPK1
MAPK10
MAPK3
MAPT
MBD2
MDC1
MDM2
MECOM
MED25
MGMT
MIER1
MKNK1
MSH2
MSH6
MSX1
MYB
MYBL1
MYBL2
MYC
MYOD1
N4BP2
NAP1L1
NCOA1
NCOA2
NCOA3
NCOA6
NEUROG1
NFATC2
NFATC4
NFE2
NFE2L2
NFIA
NFIC
NKX2-1
NLK
NPAS2
NPAT
NR3C1
NR5A1
NUP98
ONECUT1
PARP1
PAX5
PBX1
PCMT1
PCNA
PELP1
PHOX2A
PIAS1
PIAS2
PIAS3
PLAGL1
PML
POLR2A
POU1F1
POU2F3
PPARG
PPARGC1A
PPP1R8
PPP2R2A
PRKCD
PRLR
PROX1
PSME3
PTMA
PTPRF
RAD23A
RBBP4
RBBP7
RBCK1
RELA
RNF111
RPL3
RPL35
RPS6KA1
RPS6KA3
RPS6KA5
RXRG
SERTAD1
SERTAD2
SERTAD3
SETDB1
SH3GL1
SMAD2
SMAD3
SMAD4
SND1
SNIP1
SOX9
SP100
SPI1
SPIB
SRCAP
SREBF1
SREBF2
SRF
SS18L1
STAT1
STAT2
STAT3
STAT4
STAT6
SUMO1
SUV39H1
TACC2
TAF6L
TCF12
TCF3
TDG
TFDP1
TGS1
THRA
TOPORS
TP53
TP73
TRERF1
TRIP10
TRIP4
TSPYL2
UBE2D1
UBE2I
UBTF
UIMC1
VDR
WDR77
WT1
XAF1
XRCC6
YWHAH
ZBTB17
ZBTB2
ZCCHC7
ZHX1
ZMYM2
ZMYM5
ZNF451
ZNF639
ZNFX1
156 interacting genes:
AIRE
AKT2
ANP32A
ANP32B
ASH1L
ASH2L
ATXN1
AURKA
AURKB
AURKC
BCAS3
CARM1
CBX1
CBX3
CENPM
CENPT
CENPW
CHD3
CHD4
COPS2
CREBBP
CTCFL
CUL4A
DCAF1
DDB1
DNAJC9
DNMT1
DNMT3A
DNMT3B
DPF2
DYRK1A
EED
EHMT1
EHMT2
EID1
EP300
ERCC6
ESCO1
EZH2
FANCD2
FBLIM1
GATAD2A
GATAD2B
GLYR1
GRIP1
H2AC20
H4C14
HASPIN
HAT1
HDAC1
HDAC2
HDAC3
HDAC5
HDAC6
HDAC8
HDGFL3
HNF1B
HNRNPA1
HNRNPAB
HPF1
HSPA8
ING4
JMJD6
KAT14
KAT2B
KAT5
KAT6A
KAT7
KDM1A
KDM2B
KDM4A
KDM4C
KDM6A
KDM6B
KMT2A
KMT2B
KMT2C
L3MBTL2
MAD2L1
MBD5
MLLT3
MPHOSPH8
MSL3
MYB
NAP1L1
NASP
NCOR1
NR1H4
NR3C1
NSD1
NSD2
NSD3
PAF1
PAK1
PALB2
PARP1
PARP10
PARP2
PAXIP1
PBRM1
PHF1
PHF19
PHF20
PHF8
PIKFYVE
PPM1D
PPP1CA
PPP1CB
PRDM2
PRKCA
PRKCB
PRMT1
PRMT5
PRMT7
PWWP3B
RAD51B
RAG1
RBBP4
RBBP7
RCC1
RPS6KA3
SETD1A
SETD1B
SETD2
SETD7
SETDB1
SIRT1
SIRT2
SIRT3
SIRT7
SMARCA2
SMARCA4
SMARCA5
SUV39H1
TAF15
TAF1A
TAF1B
THAP7
TLE3
TRIM33
TSSK6
UBE2D1
UBE2D2
UBE2D3
UBE2D4
UBE2E1
UBE2E3
UHRF1
UHRF2
WDR5
WWC1
YEATS4
YWHAB
YWHAG
YWHAZ
ZMYND8
Entrez ID
1387
8350
HPRD ID
02534
04155
Ensembl ID
ENSG00000005339
ENSG00000275714
Uniprot IDs
Q92793
P68431
PDB IDs
1JSP
1LIQ
1RDT
1WO3
1WO4
1WO5
1WO6
1WO7
1ZOQ
2D82
2KJE
2KWF
2L84
2L85
2LXS
2LXT
2N1A
2RNY
3DWY
3P1C
3P1D
3P1E
3P1F
3SVH
4A9K
4N3W
4N4F
4NR4
4NR5
4NR6
4NR7
4NYV
4NYW
4NYX
4OUF
4TQN
4TS8
4WHU
4YK0
5CGP
5DBM
5EIC
5ENG
5EP7
5GH9
5H85
5I83
5I86
5I89
5I8B
5I8G
5J0D
5JEM
5KTU
5KTW
5KTX
5LPJ
5LPL
5MME
5MMG
5MPK
5MPN
5MPZ
5MQE
5MQG
5MQK
5NLK
5NRW
5NU3
5OWK
5SVH
5TB6
5W0E
5W0F
5W0L
5W0Q
5XXH
6ALB
6ALC
6AXQ
6AY3
6AY5
6DMK
6ES5
6ES6
6ES7
6FQO
6FQT
6FQU
6FR0
6FRF
6QST
6SQE
6SQF
6SQM
6SXX
6YIJ
6YIK
6YIL
6YIM
7JFL
7JFM
1CS9
1CT6
1O9S
1Q3L
2B2T
2B2U
2B2V
2B2W
2C1J
2C1N
2CO0
2CV5
2FSA
2KWJ
2KWK
2L75
2LBM
2LGG
2M0O
2NDF
2NDG
2OQ6
2OT7
2OX0
2RI7
2RR4
2UXN
2V85
2V89
2VNF
2VPG
2X0L
3A1B
3AFA
3AVR
3AYW
3AZE
3AZF
3AZG
3AZH
3AZI
3AZJ
3AZK
3AZL
3AZM
3AZN
3B95
3FDT
3KMT
3KQI
3LQI
3LQJ
3MP1
3O34
3O35
3O37
3QJ6
3RIG
3RIY
3SOU
3SOW
3U31
3U3D
3U4S
3U5N
3U5O
3U5P
3UEE
3UEF
3UIG
3UII
3UIK
3V43
3W96
3W97
3W98
3W99
3WA9
3WAA
3WKJ
3X1S
3X1T
3X1U
3X1V
3ZG6
3ZVY
4A0J
4A0N
4A7J
4BD3
4C1Q
4F4U
4F56
4FWF
4HON
4I51
4L7X
4LK9
4LKA
4LLB
4LXL
4N4H
4QBQ
4QBR
4QBS
4TN7
4U68
4UP0
4UY4
4X3K
4Y6L
4YHP
4YHZ
4YM5
4YM6
4Z0R
4Z2M
5AV5
5AV6
5AV8
5AV9
5AVB
5AVC
5B24
5B2I
5B2J
5B31
5C11
5C13
5C3I
5CPI
5CPJ
5CPK
5D6Y
5DAH
5FB0
5FB1
5FFV
5GH9
5GSE
5GSU
5GT0
5GT3
5GTC
5H6Q
5H6R
5HJB
5HJC
5HJD
5HYN
5IQL
5J3V
5J9S
5JHN
5JIN
5JIY
5JJ0
5JRG
5KJH
5KJI
5KKL
5LUG
5M5G
5MR8
5NNC
5NND
5OY3
5SVX
5SVY
5SZB
5SZC
5T0K
5T0M
5T1G
5T1I
5T8R
5TBN
5TDR
5TDW
5U2J
5V21
5V22
5VA6
5VAB
5VGE
5VNB
5WFC
5WLE
5WVO
5WXG
5WXH
5WYI
5X60
5XF3
5XF4
5XF5
5XFQ
5XFR
5XNV
5XTZ
5Y0C
5Y0D
5Y20
5Y2F
5Z23
5Z30
6AXJ
6AZE
6BHD
6BHE
6BHG
6BHH
6BHI
6D07
6D08
6E83
6E86
6F6D
6HKT
6HTS
6IEU
6IIS
6IIT
6IPU
6IQ4
6JOU
6JR0
6JR1
6JXD
6K1I
6K1J
6K1K
6KE9
6KVD
6L49
6L4A
6L9H
6LA8
6LA9
6LE9
6M3V
6M44
6M4D
6M4G
6M4H
6MIL
6MIM
6MIN
6MIO
6MIQ
6R8Y
6R8Z
6R90
6R91
6R92
6R93
6R94
6T90
6T93
6UPK
6UPL
6USJ
6V2H
6V3N
6V41
6V92
6VIL
6WAV
6WW4
6YIF
6YIH
6YOV
7C0M
7CCQ
7CCR
Enriched GO Terms of Interacting Partners
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