MBD3L2 and MBD2

Data Source:
BioGRID (pull down)

		MBD3L2	MBD2
Description		methyl-CpG binding domain protein 3 like 2	methyl-CpG binding domain protein 2
Image		No pdb structure
GO Annotations	Cellular Component		Histone Deacetylase Complex Chromatin Heterochromatin Nucleus Nucleoplasm Cytosol Protein-containing Complex
	Molecular Function	Protein Binding	Satellite DNA Binding MRNA Binding Protein Binding Methyl-CpG Binding Protein Domain Specific Binding Nucleosomal DNA Binding SiRNA Binding C2H2 Zinc Finger Domain Binding
	Biological Process		Negative Regulation Of Transcription By RNA Polymerase II RDNA Heterochromatin Assembly DNA Methylation-dependent Heterochromatin Assembly Heart Development Aging Response To Mechanical Stimulus Positive Regulation Of Wnt Signaling Pathway Response To Nutrient Levels Response To Estradiol Cellular Protein-containing Complex Assembly Positive Regulation Of Chromatin Binding Regulation Of Cell Population Proliferation Maternal Behavior ATP-dependent Chromatin Remodeling Regulation Of DNA Methylation Negative Regulation Of Transcription, DNA-templated Embryonic Organ Development Cellular Response To Organic Cyclic Compound
Pathways			NoRC negatively regulates rRNA expression RNA Polymerase I Promoter Opening
Drugs
Diseases
GWAS			Allergic disease (asthma, hay fever and/or eczema) (age of onset) ( 32603359) Allergic disease (asthma, hay fever and/or eczema) (multivariate analysis) ( 32603359) Body size at age 10 ( 32376654) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Nickel levels ( 26025379) Periodontitis (Mean PAL) ( 24024966) Prostate cancer ( 29892016) Psoriasis ( 23143594)
Interacting Genes		20 interacting genes: CCDC136 CHD4 GOLGA6L9 GPRASP2 HDAC1 HDAC2 KRT27 KRT34 KRTAP6-3 MBD2 MBD3 MDFI MTA1 MTA2 POLD3 RBBP4 RBBP7 RUNDC3A SBK3 TRIML2	16 interacting genes: CREBBP DHX9 GATAD2A GATAD2B GPN1 HDAC1 HDAC2 HINFP LAMTOR3 MBD3 MBD3L1 MBD3L2 PURB RBBP4 SIN3A TBP
Entrez ID		125997	8932
HPRD ID		12139	04647
Ensembl ID		ENSG00000230522	ENSG00000134046
Uniprot IDs		Q8NHZ7	A0A024R2B8 Q9UBB5
PDB IDs			2L2L 6C1A 6C1T 6C1U 6C1V 6C2F 6CNP 6CNQ
Enriched GO Terms of Interacting Partners?
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