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MBD2
Description
methyl-CpG binding domain protein 2
Image
GO Annotations
Cellular Component
Histone Deacetylase Complex
Chromatin
Heterochromatin
Nucleus
Nucleoplasm
Cytosol
Protein-containing Complex
Molecular Function
Satellite DNA Binding
MRNA Binding
Protein Binding
Methyl-CpG Binding
Protein Domain Specific Binding
Nucleosomal DNA Binding
SiRNA Binding
C2H2 Zinc Finger Domain Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
RDNA Heterochromatin Assembly
DNA Methylation-dependent Heterochromatin Assembly
Heart Development
Aging
Response To Mechanical Stimulus
Positive Regulation Of Wnt Signaling Pathway
Response To Nutrient Levels
Response To Estradiol
Cellular Protein-containing Complex Assembly
Positive Regulation Of Chromatin Binding
Regulation Of Cell Population Proliferation
Maternal Behavior
ATP-dependent Chromatin Remodeling
Regulation Of DNA Methylation
Negative Regulation Of Transcription, DNA-templated
Embryonic Organ Development
Cellular Response To Organic Cyclic Compound
Pathways
NoRC negatively regulates rRNA expression
RNA Polymerase I Promoter Opening
Drugs
Diseases
GWAS
Allergic disease (asthma, hay fever and/or eczema) (age of onset) (
32603359
)
Allergic disease (asthma, hay fever and/or eczema) (multivariate analysis) (
32603359
)
Body size at age 10 (
32376654
)
Mean corpuscular hemoglobin (
32888494
)
Mean corpuscular volume (
32888494
)
Nickel levels (
26025379
)
Periodontitis (Mean PAL) (
24024966
)
Prostate cancer (
29892016
)
Psoriasis (
23143594
)
Interacting Genes
16 interacting genes:
CREBBP
DHX9
GATAD2A
GATAD2B
GPN1
HDAC1
HDAC2
HINFP
LAMTOR3
MBD3
MBD3L1
MBD3L2
PURB
RBBP4
SIN3A
TBP
Entrez ID
8932
HPRD ID
04647
Ensembl ID
ENSG00000134046
Uniprot IDs
A0A024R2B8
Q9UBB5
PDB IDs
2L2L
6C1A
6C1T
6C1U
6C1V
6C2F
6CNP
6CNQ
Enriched GO Terms of Interacting Partners
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