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CCR1 and CCL15
Data Source:
HPRD
(in vivo)
CCR1
CCL15
Description
C-C motif chemokine receptor 1
C-C motif chemokine ligand 15
Image
GO Annotations
Cellular Component
Cytoplasm
Plasma Membrane
Integral Component Of Plasma Membrane
External Side Of Plasma Membrane
Extracellular Space
Molecular Function
Phosphatidylinositol Phospholipase C Activity
Chemokine Receptor Activity
Protein Binding
C-C Chemokine Receptor Activity
C-C Chemokine Binding
Chemokine (C-C Motif) Ligand 7 Binding
Chemokine (C-C Motif) Ligand 5 Binding
Signaling Receptor Binding
Chemokine Activity
Heparin Binding
Chemoattractant Activity
CCR Chemokine Receptor Binding
Biological Process
Dendritic Cell Chemotaxis
Calcium Ion Transport
Cellular Calcium Ion Homeostasis
Exocytosis
Chemotaxis
Inflammatory Response
Immune Response
Cell Adhesion
Cell Surface Receptor Signaling Pathway
G Protein-coupled Receptor Signaling Pathway
G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger
Positive Regulation Of Cytosolic Calcium Ion Concentration
Cell-cell Signaling
Response To Wounding
Negative Regulation Of Gene Expression
Cytokine-mediated Signaling Pathway
Calcium-mediated Signaling
Positive Regulation Of Cell Migration
Negative Regulation Of Bone Mineralization
Positive Regulation Of Osteoclast Differentiation
Positive Regulation Of Calcium Ion Transport
Cell Chemotaxis
Chemokine-mediated Signaling Pathway
Positive Regulation Of ERK1 And ERK2 Cascade
Positive Regulation Of Monocyte Chemotaxis
Monocyte Chemotaxis
Cellular Calcium Ion Homeostasis
Chemotaxis
Inflammatory Response
Signal Transduction
G Protein-coupled Receptor Signaling Pathway
Cell-cell Signaling
Neutrophil Chemotaxis
Positive Regulation Of GTPase Activity
Lymphocyte Chemotaxis
Positive Chemotaxis
Chemokine-mediated Signaling Pathway
Positive Regulation Of ERK1 And ERK2 Cascade
Cellular Response To Interferon-gamma
Cellular Response To Interleukin-1
Cellular Response To Tumor Necrosis Factor
Pathways
Chemokine receptors bind chemokines
G alpha (i) signalling events
Interleukin-10 signaling
Drugs
Diseases
GWAS
Arthritis (juvenile idiopathic) (
33106285
)
Behcet's disease (
23291587
)
Celiac disease (
22057235
20190752
30572963
18311140
)
Celiac disease and Rheumatoid arthritis (
26546613
)
Heel bone mineral density (
30598549
)
Inflammatory bowel disease (
26192919
)
Juvenile idiopathic arthritis (oligoarticular or rheumatoid factor-negative polyarticular) (
23603761
)
Narcolepsy with cataplexy (
25986216
)
Ulcerative colitis (
26192919
28067908
)
Blood protein levels (
29875488
28240269
)
Neonatal cytokine/chemokine levels (fetal genetic effect) (
30134952
)
Upper eyelid sagging severity (
24869959
)
Interacting Genes
29 interacting genes:
CCL14
CCL15
CCL16
CCL2
CCL23
CCL26
CCL3
CCL3L1
CCL4
CCL5
CCL7
CCL8
CD74
CREB3
FAN1
GNA14
GRAMD1A
JAK1
LETMD1
MBP
PLP2
PRNP
QSOX1
STAT1
STAT3
TMEFF1
TMX1
TPST1
TPST2
3 interacting genes:
CCL2
CCR1
CCR3
Entrez ID
1230
6359
HPRD ID
03101
03232
Ensembl ID
ENSG00000163823
ENSG00000275718
Uniprot IDs
P32246
Q5U003
A0A0B4J2E2
Q16663
PDB IDs
1Y5D
2HCC
Enriched GO Terms of Interacting Partners
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