CCL15 and CCR3

Data Source:
HPRD (in vivo)

		CCL15	CCR3
Description		C-C motif chemokine ligand 15	C-C motif chemokine receptor 3
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Space	Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane
	Molecular Function	Signaling Receptor Binding Chemokine Activity Heparin Binding Chemoattractant Activity CCR Chemokine Receptor Binding	Chemokine Receptor Activity Protein Binding C-C Chemokine Receptor Activity C-C Chemokine Binding
	Biological Process	Monocyte Chemotaxis Cellular Calcium Ion Homeostasis Chemotaxis Inflammatory Response Signal Transduction G Protein-coupled Receptor Signaling Pathway Cell-cell Signaling Neutrophil Chemotaxis Positive Regulation Of GTPase Activity Lymphocyte Chemotaxis Positive Chemotaxis Chemokine-mediated Signaling Pathway Positive Regulation Of ERK1 And ERK2 Cascade Cellular Response To Interferon-gamma Cellular Response To Interleukin-1 Cellular Response To Tumor Necrosis Factor	Positive Regulation Of Endothelial Cell Proliferation Chemotaxis Inflammatory Response Immune Response Cellular Defense Response Cell Adhesion G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Viral Process Calcium-mediated Signaling Positive Regulation Of Angiogenesis Cell Chemotaxis Chemokine-mediated Signaling Pathway
Pathways			Chemokine receptors bind chemokines G alpha (i) signalling events
Drugs
Diseases
GWAS		Blood protein levels ( 29875488 28240269) Neonatal cytokine/chemokine levels (fetal genetic effect) ( 30134952) Upper eyelid sagging severity ( 24869959)	Arthritis (juvenile idiopathic) ( 33106285) Basophil count ( 32888494) Basophil percentage of granulocytes ( 27863252) Basophil percentage of white cells ( 32888494 27863252) Behcet's disease ( 23291587) Blood protein levels ( 28240269) Bone mineral density (Ward's triangle area) ( 27397699) Celiac disease ( 22057235 20190752 25920553 24999842 18311140) Celiac disease and Rheumatoid arthritis ( 26546613) Cerebrospinal fluid levels of Alzheimer's disease-related proteins ( 25340798) Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494) Inflammatory bowel disease ( 26192919) Juvenile idiopathic arthritis (oligoarticular or rheumatoid factor-negative polyarticular) ( 23603761) Monocyte chemoattractant protein-1 levels ( 23017229) Monocyte count ( 29403010 27863252) Narcolepsy with cataplexy ( 25986216) Obesity-related traits ( 23251661) Ulcerative colitis ( 26192919 28067908) White blood cell count (basophil) ( 27863252)
Interacting Genes		3 interacting genes: CCL2 CCR1 CCR3	19 interacting genes: CCL11 CCL13 CCL14 CCL15 CCL2 CCL24 CCL26 CCL28 CCL3 CCL3L1 CCL4 CCL5 CCL7 CCL8 CXCL10 CXCL11 CXCL9 FGR HCK
Entrez ID		6359	1232
HPRD ID		03232	03167
Ensembl ID		ENSG00000275718	ENSG00000183625
Uniprot IDs		A0A0B4J2E2 Q16663	A1LPE5 P51677 Q8TDP4 Q8TDP5
PDB IDs		2HCC
Enriched GO Terms of Interacting Partners?
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