CLCN1 and CIDEB

Data Source:
BioGRID (two hybrid)

		CLCN1	CIDEB
Description		chloride voltage-gated channel 1	cell death inducing DFFA like effector b
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GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Chloride Channel Complex Sarcolemma	Cytosol Perinuclear Region Of Cytoplasm
	Molecular Function	Voltage-gated Chloride Channel Activity Protein Binding Protein Homodimerization Activity	Protein Binding Identical Protein Binding
	Biological Process	Chloride Transport Muscle Contraction Neuronal Action Potential Propagation Ion Transmembrane Transport Regulation Of Ion Transmembrane Transport Chloride Transmembrane Transport	Apoptotic Process Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Positive Regulation Of Cell Death Viral Process Response To Nutrient Levels Bile Acid Signaling Pathway Regulation Of Apoptotic Process Positive Regulation Of Release Of Cytochrome C From Mitochondria Execution Phase Of Apoptosis Activation Of Cysteine-type Endopeptidase Activity
Pathways		Stimuli-sensing channels
Drugs
Diseases		Myotonia congenita, including: Autosomal dominant myotonia congenita (Thomsen disease); Autosomal recessive myotonia congenita (Becker disease); Fluctuating myotonia congenita; Myotonia levoir
GWAS			Anorectal malformation ( 31136621) Height ( 28552196) Parent of origin effect on language impairment (paternal) ( 24571439)
Interacting Genes		7 interacting genes: AHSA1 APPBP2 CIDEB FAM9B FKBP8 PRDM5 STIP1	68 interacting genes: ABHD16A AFG1L APOC1 ARL8B ATP5ME ATP5MJ BCL2L2 C5orf38 CAND2 CIDEA CLCN1 CMPK1 COL10A1 COL8A1 COX7C DFFA DFFB DHRSX DNAJA3 FAM218A FAM47E-STBD1 FKBP8 FOXD4L3 FUNDC2 GCSH GNB3 GPAM H4C7 HAPLN2 HCCS HIGD1C MEST MICOS10 MPC2 MRPL36 MRPL57 MTERF4 NAALAD2 NDRG4 NFU1 NME4 PBX3 PDHX PGLYRP3 PISD PPIF RAMP2 RHBDD2 ROMO1 RTP5 SAA2 SAA4 SAR1B SCO1 SCO2 SDHAF1 SFXN1 SMARCC1 SPG21 TAOK2 TBX2 TEX44 THBD TIMM17B TMEM14B TPRG1 TSR1 UFSP1
Entrez ID		1180	27141
HPRD ID		00320	11981
Ensembl ID		ENSG00000188037	ENSG00000136305
Uniprot IDs		P35523	Q9UHD4
PDB IDs		6COY 6COZ 6QV6 6QVB 6QVC 6QVD 6QVU	1D4B
Enriched GO Terms of Interacting Partners?
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