CHRND and CHRNA1

Data Source:
HPRD (in vitro)

		CHRND	CHRNA1
Description		cholinergic receptor nicotinic delta subunit	cholinergic receptor nicotinic alpha 1 subunit
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytosol Plasma Membrane Integral Component Of Plasma Membrane Acetylcholine-gated Channel Complex Neuromuscular Junction Neuron Projection Synapse Postsynaptic Membrane Integral Component Of Postsynaptic Specialization Membrane	Plasma Membrane Integral Component Of Plasma Membrane Acetylcholine-gated Channel Complex Cell Surface Neuromuscular Junction Neuron Projection Synapse Postsynaptic Membrane Integral Component Of Postsynaptic Specialization Membrane
	Molecular Function	Transmembrane Signaling Receptor Activity Acetylcholine-gated Cation-selective Channel Activity Neurotransmitter Receptor Activity Acetylcholine Binding Transmitter-gated Ion Channel Activity Involved In Regulation Of Postsynaptic Membrane Potential	Ion Channel Activity Acetylcholine Receptor Activity Acetylcholine-gated Cation-selective Channel Activity Neurotransmitter Receptor Activity Acetylcholine Binding Transmitter-gated Ion Channel Activity Involved In Regulation Of Postsynaptic Membrane Potential
	Biological Process	Skeletal Muscle Contraction Cation Transport Muscle Contraction Signal Transduction Chemical Synaptic Transmission Ion Transmembrane Transport Regulation Of Membrane Potential Skeletal Muscle Tissue Growth Nervous System Process Musculoskeletal Movement Neuromuscular Process Excitatory Postsynaptic Potential	Skeletal Muscle Contraction Cation Transport Signal Transduction Chemical Synaptic Transmission Synaptic Transmission, Cholinergic Neuromuscular Synaptic Transmission Neuromuscular Junction Development Neuronal Action Potential Ion Transmembrane Transport Regulation Of Membrane Potential Muscle Cell Cellular Homeostasis Skeletal Muscle Tissue Growth Nervous System Process Musculoskeletal Movement Neuromuscular Process Excitatory Postsynaptic Potential Neuron Cellular Homeostasis
Pathways		Highly sodium permeable postsynaptic acetylcholine nicotinic receptors	Highly calcium permeable postsynaptic nicotinic acetylcholine receptors Highly calcium permeable nicotinic acetylcholine receptors
Drugs			Lamotrigine Agmatine
Diseases		Congenital myasthenic syndrome Multiple pterygium syndrome, including: Multiple pterygium syndrome, lethal type (LMPS); Multiple pterygium syndrome, Escobar variant (EVMPS)	Congenital myasthenic syndrome Multiple pterygium syndrome, including: Multiple pterygium syndrome, lethal type (LMPS); Multiple pterygium syndrome, Escobar variant (EVMPS)
GWAS		Brain lesion load ( 19010793) Refractive error ( 32231278)	Atrial fibrillation ( 29892015)
Interacting Genes		2 interacting genes: CHRNA1 GRB2	5 interacting genes: CHRND CHRNE CHRNG ITGA7 LILRB3
Entrez ID		1144	1134
HPRD ID		01516	00007
Ensembl ID		ENSG00000135902	ENSG00000138435
Uniprot IDs		B4E3W4 Q07001	P02708 Q53SH4
PDB IDs			1Y5P 1Y5T 1Y6C 4ZJS 5HBT
Enriched GO Terms of Interacting Partners?
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