RAB31 and ALS2CL

Data Source:
BioGRID (two hybrid)

		RAB31	ALS2CL
Description		RAB31, member RAS oncogene family	ALS2 C-terminal like
Image			No pdb structure
GO Annotations	Cellular Component	Phagocytic Cup Early Endosome Cytosol Plasma Membrane Endomembrane System Secretory Granule Membrane Early Endosome Membrane Trans-Golgi Network Membrane Early Phagosome Membrane Phagocytic Vesicle	Cytosol
	Molecular Function	GTPase Activity Protein Binding GTP Binding GDP Binding	GTPase Activator Activity Protein Binding Identical Protein Binding
	Biological Process	Intracellular Protein Transport Receptor Internalization Cellular Response To Insulin Stimulus Golgi To Plasma Membrane Protein Transport Neutrophil Degranulation Regulated Exocytosis Positive Regulation Of Phagocytosis, Engulfment Phagosome Maturation	Endosome Organization Positive Regulation Of GTPase Activity
Pathways		Neutrophil degranulation RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs	RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS		Age at first sexual intercourse ( 27089180) Basophil count ( 32888494) Blood pressure (age interaction) ( 24954895) Bone fracture in osteoporosis ( 28580392) Dupuytren's disease ( 28886342) Lung adenocarcinoma ( 28604730)
Interacting Genes		6 interacting genes: ALS2CL EEA1 EGFR MAPK6 MPP3 OCRL	7 interacting genes: EEF1AKMT3 PPP1R32 RAB22A RAB31 RAB5A RAB5C RSPH14
Entrez ID		11031	259173
HPRD ID		05751	10643
Ensembl ID		ENSG00000168461	ENSG00000178038
Uniprot IDs		Q13636	A0A024R2U1 Q60I27
PDB IDs		2FG5
Enriched GO Terms of Interacting Partners?
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