ALS2CL and RAB22A

		ALS2CL	RAB22A
Description		ALS2 C-terminal like	RAB22A, member RAS oncogene family
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol	Ruffle Early Endosome Late Endosome Plasma Membrane Endosome Membrane Endomembrane System Actin Cytoskeleton Phagocytic Vesicle Membrane Phagocytic Vesicle Extracellular Exosome
	Molecular Function	GTPase Activator Activity Protein Binding Identical Protein Binding	GTPase Activity Protein Binding GTP Binding GDP Binding
	Biological Process	Endosome Organization Positive Regulation Of GTPase Activity	Intracellular Protein Transport Endocytosis Endosome Organization Regulation Of Vesicle Size
Pathways		RAB GEFs exchange GTP for GDP on RABs	RAB geranylgeranylation
Drugs
Diseases
GWAS			Change in LVEF in response to paclitaxel and trastuzumab in HER2+ breast cancer ( 28763429) Metabolite levels ( 23823483) Nickel levels ( 26025379)
Interacting Genes		7 interacting genes: EEF1AKMT3 PPP1R32 RAB22A RAB31 RAB5A RAB5C RSPH14	7 interacting genes: ALS2CL APPL2 EEA1 RAB3GAP1 RAB7A RABAC1 SMURF2
Entrez ID		259173	57403
HPRD ID		10643	06696
Ensembl ID		ENSG00000178038	ENSG00000124209
Uniprot IDs		A0A024R2U1 Q60I27	Q9UL26
PDB IDs
Enriched GO Terms of Interacting Partners?
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