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PGRMC1 and BIK
Data Source:
BioGRID
(two hybrid)
PGRMC1
BIK
Description
progesterone receptor membrane component 1
BCL2 interacting killer
Image
GO Annotations
Cellular Component
Mitochondrial Outer Membrane
Endoplasmic Reticulum
Plasma Membrane
Integral Component Of Plasma Membrane
Endomembrane System
Membrane
Smooth Endoplasmic Reticulum Membrane
Specific Granule Membrane
Neuron Projection
Neuronal Cell Body
Cell Body
Synapse
Endomembrane System
Integral Component Of Membrane
Mitochondrial Membrane
Molecular Function
Amyloid-beta Binding
Steroid Binding
Protein Binding
Heme Binding
Protein Homodimerization Activity
Metal Ion Binding
Protein Binding
Biological Process
Heme Biosynthetic Process
Neutrophil Degranulation
Apoptotic Process
Male Gonad Development
Apoptotic Mitochondrial Changes
Positive Regulation Of Protein-containing Complex Assembly
Regulation Of Apoptotic Process
Positive Regulation Of Release Of Cytochrome C From Mitochondria
Pathways
Neutrophil degranulation
Drugs
Dextromethorphan
Nortriptyline
Sertraline
Diseases
GWAS
Prostate cancer (
25939597
21743057
)
Prostate cancer (SNP x SNP interaction) (
22219177
)
Interacting Genes
20 interacting genes:
BIK
CAMLG
CCDC134
CENPU
CIAO1
CREB3L1
DEFB124
EVI2B
GET3
GLP1R
GOLM1
KASH5
KCNE5
MTNR1A
PAM16
PGRMC2
SCAP
SGTB
TMEM213
ZNF71
95 interacting genes:
ADGRE2
ADIPOQ
AIG1
ALG8
ANKRD46
APOD
APP
ASB11
BCL2
BCL2A1
BCL2L1
BCL2L10
BCL2L2
BMP10
BNIP3
BRICD5
BTN2A2
C14orf180
C3orf52
C4orf3
CD53
CD72
CLDN19
CMTM5
CMTM7
CNIH1
CNIH3
CREB3
CRKL
CTXN3
CXCL16
CYB561
CYB5B
ELOVL4
ERGIC3
EXOC3L2
FAM209A
FAM241B
FAM3C
FATE1
FCGR1A
GPX8
GRM2
INSIG2
KCNN4
MARCHF5
MCL1
MS4A13
NAT8
NR2F2
NRM
PBX3
PGAP2
PGRMC1
PLN
PLP1
PLP2
PLPP4
REEP4
RUSF1
S100A1
SCAMP4
SEC22A
SELENOK
SERP1
SERP2
SLC35E3
SLC37A4
SLC39A7
SMIM1
SOCS3
STRIT1
STX8
TANK
TMBIM1
TMEM107
TMEM11
TMEM14B
TMEM14C
TMEM199
TMEM222
TMEM229B
TMEM243
TMEM254
TMEM60
TMEM80
TMEM86B
TMEM97
TRARG1
TSPO2
UBE2D1
UBIAD1
VAMP3
VAMP5
ZFPL1
Entrez ID
10857
638
HPRD ID
02338
04547
Ensembl ID
ENSG00000101856
ENSG00000100290
Uniprot IDs
O00264
Q6IB11
A0A024R4X6
Q13323
PDB IDs
4X8Y
2IPE
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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