PGRMC1 and PAM16

Data Source:
BioGRID (two hybrid)

		PGRMC1	PAM16
Description		progesterone receptor membrane component 1	presequence translocase associated motor 16
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrial Outer Membrane Endoplasmic Reticulum Plasma Membrane Integral Component Of Plasma Membrane Endomembrane System Membrane Smooth Endoplasmic Reticulum Membrane Specific Granule Membrane Neuron Projection Neuronal Cell Body Cell Body Synapse	PAM Complex, Tim23 Associated Import Motor TIM23 Mitochondrial Import Inner Membrane Translocase Complex Mitochondrial Matrix Extrinsic Component Of Mitochondrial Inner Membrane Protein-containing Complex
	Molecular Function	Amyloid-beta Binding Steroid Binding Protein Binding Heme Binding Protein Homodimerization Activity Metal Ion Binding	Protein Binding
	Biological Process	Heme Biosynthetic Process Neutrophil Degranulation	Ossification Protein Import Into Mitochondrial Matrix Negative Regulation Of ATPase Activity
Pathways		Neutrophil degranulation	Mitochondrial protein import
Drugs		Dextromethorphan Nortriptyline Sertraline
Diseases
GWAS			Erectile dysfunction ( 30583798)
Interacting Genes		20 interacting genes: BIK CAMLG CCDC134 CENPU CIAO1 CREB3L1 DEFB124 EVI2B GET3 GLP1R GOLM1 KASH5 KCNE5 MTNR1A PAM16 PGRMC2 SCAP SGTB TMEM213 ZNF71	10 interacting genes: ARL6IP1 BLOC1S2 CEP70 DNAJC19 DNMT3B FEZ1 GPM6A MEOX2 MRFAP1 PGRMC1
Entrez ID		10857	51025
HPRD ID		02338	14798
Ensembl ID		ENSG00000101856	ENSG00000217930
Uniprot IDs		O00264 Q6IB11	Q9Y3D7
PDB IDs		4X8Y
Enriched GO Terms of Interacting Partners?
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