NOXA1 and ZNF474

Data Source:
BioGRID (two hybrid)

		NOXA1	ZNF474
Description		NADPH oxidase activator 1	zinc finger protein 474
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol NADPH Oxidase Complex
	Molecular Function	Protein Binding Superoxide-generating NADPH Oxidase Activator Activity SH3 Domain Binding Enzyme Binding Small GTPase Binding	Protein Binding Metal Ion Binding
	Biological Process	Superoxide Metabolic Process Regulation Of Hydrogen Peroxide Metabolic Process Superoxide Anion Generation Regulation Of Catalytic Activity Regulation Of Respiratory Burst
Pathways		RHO GTPases Activate NADPH Oxidases WNT5:FZD7-mediated leishmania damping
Drugs
Diseases
GWAS		Response to fenofibrate (total cholesterol levels) ( 27002377)	Intraocular pressure ( 29617998)
Interacting Genes		57 interacting genes: ANKRD55 C19orf54 C9orf24 CACNA1A CEP70 CFP CRYBA1 CTDSP1 CYSRT1 DCLRE1B DDAH2 DUSP4 EP300 FAT1 GATAD2B IL16 KCTD15 KRTAP13-1 KRTAP15-1 KRTAP19-4 KRTAP19-7 KRTAP8-1 LASP1 LMO2 MAPK1 MAPK11 METTL27 MORN3 MYLIP NAA10 NADSYN1 NCF1 NDUFAB1 NOX1 NOXO1 PFDN5 PLA2G10 PRKACA PRKCA PRKCG QARS1 RAC1 RAC2 REL RIMBP3 RIMBP3C SMUG1 TCF19 TCF4 TGS1 TRAF2 TRIM23 UBAP2 WDR83 ZC2HC1C ZNF474 ZNF620	29 interacting genes: ABI2 ATP6V0D2 BANP C2CD6 CABP5 CCDC57 COMMD8 CPNE7 CTNNA3 FRMD8 GPATCH11 GRB2 GYS1 IL16 KCTD7 MCMBP MLH1 NOXA1 PFKFB1 PPL PRKAB2 RSPH14 SEPHS1 TCF19 TEKT4 TRIM23 TSR2 UBASH3A ZIC1
Entrez ID		10811	133923
HPRD ID		17644	13411
Ensembl ID		ENSG00000188747	ENSG00000164185
Uniprot IDs		Q86UR1	Q6S9Z5
PDB IDs
Enriched GO Terms of Interacting Partners?
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