CGRRF1 and AGR3

Data Source:
BioGRID (two hybrid)

		CGRRF1	AGR3
Description		cell growth regulator with ring finger domain 1	anterior gradient 3, protein disulphide isomerase family member
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GO Annotations	Cellular Component	Nucleoplasm Endoplasmic Reticulum Intracellular Membrane-bounded Organelle	Endoplasmic Reticulum Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding Metal Ion Binding	Dystroglycan Binding Protein Binding
	Biological Process	Cell Cycle Arrest Negative Regulation Of Cell Population Proliferation Negative Regulation Of Cell Growth	Biological_process Negative Regulation Of Cell Death
Pathways
Drugs
Diseases
GWAS		Dental caries ( 23259602) Monobrow thickness ( 26926045) Night sleep phenotypes ( 27126917)	Coffee consumption ( 31959922 29367735) Cutaneous malignant melanoma ( 32341527 26237428) Cutaneous squamous cell carcinoma ( 32041948) Diffusing capacity of carbon monoxide ( 30694715) Lung cancer in ever smokers ( 28604730) Melanoma ( 28212542) Refractive error ( 32231278) Residual cognition ( 28441426) Rosacea symptom severity ( 29771307) Type 2 diabetes (dietary heme iron intake interaction) ( 23386860) Urinary albumin excretion ( 30220432) Urinary albumin excretion (no hypertensive medication) ( 30220432)
Interacting Genes		32 interacting genes: AGR3 BET1 CD72 CDIPT CREB3 CYB5B FAM241B FAXDC2 FFAR2 GPR151 GPR152 JAGN1 KLRC1 LAPTM4B LNPEP MARCHF5 MTIF3 PEX10 PGAP2 RHBDD1 SCAMP4 SLC30A3 SLC30A8 SUSD3 TMEM140 TMEM187 TMEM31 TMEM97 TPRG1 UBE2U YIPF6 ZFPL1	35 interacting genes: AKT1 AP1B1 APC ASB10 BCAR3 CASP8 CATSPER1 CD46 CGRRF1 CNNM3 DAG1 DESI1 EDA2R ERLIN1 ESR2 FXYD3 KRTAP11-1 LIME1 LSM1 LYPD3 MMGT1 NRM NTAQ1 NUP62 PDZK1IP1 PRAF2 PTPN1 SGTA SGTB SPINT1 TGFB1 TIMMDC1 TMEM14B UBQLN1 UBQLN2
Entrez ID		10668	155465
HPRD ID		09366	16545
Ensembl ID		ENSG00000100532	ENSG00000173467
Uniprot IDs		Q99675	Q8TD06
PDB IDs		2EA5	3PH9
Enriched GO Terms of Interacting Partners?
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