CGRRF1 and LAPTM4B

Data Source:
BioGRID (two hybrid)

		CGRRF1	LAPTM4B
Description		cell growth regulator with ring finger domain 1	lysosomal protein transmembrane 4 beta
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Endoplasmic Reticulum Intracellular Membrane-bounded Organelle	Lysosome Lysosomal Membrane Endosome Early Endosome Plasma Membrane Integral Component Of Membrane Late Endosome Membrane Multivesicular Body Membrane Cell Projection Multivesicular Body, Internal Vesicle
	Molecular Function	Protein Binding Metal Ion Binding	Protein Binding Kinase Binding Ubiquitin Protein Ligase Binding Ceramide Binding Phosphatidylinositol Bisphosphate Binding
	Biological Process	Cell Cycle Arrest Negative Regulation Of Cell Population Proliferation Negative Regulation Of Cell Growth	Endosome Organization Endosome Transport Via Multivesicular Body Sorting Pathway Negative Regulation Of Transforming Growth Factor Beta1 Production Regulation Of Lysosomal Membrane Permeability Negative Regulation Of Lysosomal Protein Catabolic Process Regulation Of Lysosome Organization
Pathways
Drugs
Diseases
GWAS		Dental caries ( 23259602) Monobrow thickness ( 26926045) Night sleep phenotypes ( 27126917)	Metabolite levels ( 23823483) QT interval ( 24952745)
Interacting Genes		32 interacting genes: AGR3 BET1 CD72 CDIPT CREB3 CYB5B FAM241B FAXDC2 FFAR2 GPR151 GPR152 JAGN1 KLRC1 LAPTM4B LNPEP MARCHF5 MTIF3 PEX10 PGAP2 RHBDD1 SCAMP4 SLC30A3 SLC30A8 SUSD3 TMEM140 TMEM187 TMEM31 TMEM97 TPRG1 UBE2U YIPF6 ZFPL1	21 interacting genes: BDKRB1 CGRRF1 CTXN3 CYB561A3 EMP1 GJA8 GPX8 IFNAR1 IGFBP5 ISLR2 MTIF3 NAALADL2 NRG1 ODF4 PIP5K1C SCARB2 SLC22A1 SLC22A2 SLC29A2 TMEM86B TRARG1
Entrez ID		10668	55353
HPRD ID		09366	13960
Ensembl ID		ENSG00000100532	ENSG00000104341
Uniprot IDs		Q99675	Q86VI4
PDB IDs		2EA5
Enriched GO Terms of Interacting Partners?
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