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POLR3F and NINL
Data Source:
BioGRID
(affinity chromatography technology)
POLR3F
NINL
Description
RNA polymerase III subunit F
ninein like
Image
No pdb structure
GO Annotations
Cellular Component
Nucleoplasm
RNA Polymerase III Complex
Cytosol
Centrosome
Cytosol
Microtubule
Microtubule Cytoskeleton
Intercellular Bridge
Molecular Function
Double-stranded DNA Binding
DNA-directed 5'-3' RNA Polymerase Activity
Protein Binding
Calcium Ion Binding
Protein Binding
Biological Process
Regulation Of Transcription By RNA Polymerase III
Transcription By RNA Polymerase III
Positive Regulation Of Type I Interferon Production
Positive Regulation Of Interferon-beta Production
Innate Immune Response
Positive Regulation Of Innate Immune Response
Defense Response To Virus
G2/M Transition Of Mitotic Cell Cycle
Regulation Of G2/M Transition Of Mitotic Cell Cycle
Microtubule Anchoring At Centrosome
Ciliary Basal Body-plasma Membrane Docking
Pathways
Cytosolic sensors of pathogen-associated DNA
RNA Polymerase III Chain Elongation
RNA Polymerase III Transcription Termination
RNA Polymerase III Abortive And Retractive Initiation
RNA Polymerase III Transcription Initiation From Type 1 Promoter
RNA Polymerase III Transcription Initiation From Type 1 Promoter
RNA Polymerase III Transcription Initiation From Type 2 Promoter
RNA Polymerase III Transcription Initiation From Type 2 Promoter
RNA Polymerase III Transcription Initiation From Type 3 Promoter
RNA Polymerase III Transcription Initiation From Type 3 Promoter
Regulation of PLK1 Activity at G2/M Transition
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
Anchoring of the basal body to the plasma membrane
AURKA Activation by TPX2
Drugs
Diseases
GWAS
Refractive error (
32231278
)
Brain morphology (MOSTest) (
32665545
)
Macular thickness (
30535121
)
Telomere length (
30185882
)
Urate levels (
31578528
)
Interacting Genes
15 interacting genes:
ATPAF2
BDP1
BRF1
ERG28
GTF3C4
KAT5
LRIF1
PRPF4B
RIN3
STC2
SUV39H2
TBP
TNS2
UBE2G2
WDR89
51 interacting genes:
AKAP17A
APEX2
AURKB
CBY2
CCDC130
CCDC146
CCDC33
CCHCR1
CLEC1B
DCTN5
ELOA
ERBB2
EWSR1
EZH2
FAM107A
FAM161A
GCC1
GPKOW
HAUS1
JUNB
KANSL1
KAT5
KAT7
KRT1
L3MBTL4
LRSAM1
LZTS2
MAD1L1
MBIP
MCM10
PLK1
PRPF18
PRPF3
RBM41
RCOR3
RGS2
RIBC2
RNF40
SH2D4A
SH3BP5L
SYT17
TCEANC
TNNT1
TSPYL4
UTP14A
ZFC3H1
ZFHX3
ZNF250
ZNF417
ZNF426
ZNF646
Entrez ID
10621
22981
HPRD ID
15156
11120
Ensembl ID
ENSG00000132664
ENSG00000101004
Uniprot IDs
Q05DB8
Q9H1D9
Q9Y2I6
PDB IDs
2DK5
2YU3
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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