POLR3F and PRPF4B

Data Source:
BioGRID (affinity chromatography technology)
HPRD (two hybrid)

		POLR3F	PRPF4B
Description		RNA polymerase III subunit F	pre-mRNA processing factor 4B
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GO Annotations	Cellular Component	Nucleoplasm RNA Polymerase III Complex Cytosol	Nucleus Chromosome Nuclear Speck Catalytic Step 2 Spliceosome
	Molecular Function	Double-stranded DNA Binding DNA-directed 5'-3' RNA Polymerase Activity Protein Binding	RNA Binding Protein Kinase Activity Protein Binding ATP Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity
	Biological Process	Regulation Of Transcription By RNA Polymerase III Transcription By RNA Polymerase III Positive Regulation Of Type I Interferon Production Positive Regulation Of Interferon-beta Production Innate Immune Response Positive Regulation Of Innate Immune Response Defense Response To Virus	MRNA Splicing, Via Spliceosome Protein Phosphorylation RNA Splicing MRNA Cis Splicing, Via Spliceosome
Pathways		Cytosolic sensors of pathogen-associated DNA RNA Polymerase III Chain Elongation RNA Polymerase III Transcription Termination RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter
Drugs			Fostamatinib
Diseases
GWAS		Refractive error ( 32231278)	Night sleep phenotypes ( 27126917)
Interacting Genes		15 interacting genes: ATPAF2 BDP1 BRF1 ERG28 GTF3C4 KAT5 LRIF1 PRPF4B RIN3 STC2 SUV39H2 TBP TNS2 UBE2G2 WDR89	8 interacting genes: CLK1 HSPB3 KLF13 PNN POLR3F SRPK2 SRSF1 YWHAG
Entrez ID		10621	8899
HPRD ID		15156	09087
Ensembl ID		ENSG00000132664	ENSG00000112739
Uniprot IDs		Q05DB8 Q9H1D9	A0A024QZY5 Q13523
PDB IDs		2DK5 2YU3	4IAN 4IFC 4IIR 4IJP 6CNH 6PJJ 6PK6 6QX9
Enriched GO Terms of Interacting Partners?
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