NINL and SYT17

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		NINL	SYT17
Description		ninein like	synaptotagmin 17
Image		No pdb structure
GO Annotations	Cellular Component	Centrosome Cytosol Microtubule Microtubule Cytoskeleton Intercellular Bridge	Plasma Membrane Exocytic Vesicle
	Molecular Function	Calcium Ion Binding Protein Binding	SNARE Binding Phosphatidylserine Binding Calcium Ion Binding Protein Binding Calcium-dependent Phospholipid Binding Syntaxin Binding Clathrin Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Regulation Of G2/M Transition Of Mitotic Cell Cycle Microtubule Anchoring At Centrosome Ciliary Basal Body-plasma Membrane Docking	Regulation Of Dopamine Secretion Vesicle-mediated Transport Calcium-ion Regulated Exocytosis Regulation Of Calcium Ion-dependent Exocytosis Cell Differentiation Cellular Response To Calcium Ion Positive Regulation Of Dendrite Extension
Pathways		Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Macular thickness ( 30535121) Telomere length ( 30185882) Urate levels ( 31578528)	Alcohol dependence ( 21876473) Fruit consumption ( 32066663) Parkinson's disease ( 27182965) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892)
Interacting Genes		51 interacting genes: AKAP17A APEX2 AURKB CBY2 CCDC130 CCDC146 CCDC33 CCHCR1 CLEC1B DCTN5 ELOA ERBB2 EWSR1 EZH2 FAM107A FAM161A GCC1 GPKOW HAUS1 JUNB KANSL1 KAT5 KAT7 KRT1 L3MBTL4 LRSAM1 LZTS2 MAD1L1 MBIP MCM10 PLK1 PRPF18 PRPF3 RBM41 RCOR3 RGS2 RIBC2 RNF40 SH2D4A SH3BP5L SYT17 TCEANC TNNT1 TSPYL4 UTP14A ZFC3H1 ZFHX3 ZNF250 ZNF417 ZNF426 ZNF646	50 interacting genes: AK8 APP APTX BLZF1 CBY2 CCDC102B CCDC33 CCDC85B CCNB1IP1 CEP63 CEP70 CHMP4A COG6 DEPDC5 EXOC8 FAM9B FRMD6 GMCL1 GOLGA2 GOLGA6A HIP1 HOOK2 IKZF1 LSM7 LZTS1 LZTS2 MAD1L1 MAJIN MCC MEOX1 MEOX2 MID2 NIF3L1 NINL PFDN5 PIBF1 PICK1 POF1B RUNDC3A SDCBP2 SNRNP35 SSX2IP TRAF2 TRIM27 TSC22D4 TSNAX VPS9D1 ZNF438 ZNF597 ZRANB1
Entrez ID		22981	51760
HPRD ID		11120	17425
Ensembl ID		ENSG00000101004	ENSG00000103528
Uniprot IDs		Q9Y2I6	H3BN78 H3BRH9 Q9BSW7
PDB IDs			2ENP
Enriched GO Terms of Interacting Partners?
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