POLR3F and UBE2G2

Data Source:
BioGRID (two hybrid)

		POLR3F	UBE2G2
Description		RNA polymerase III subunit F	ubiquitin conjugating enzyme E2 G2
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GO Annotations	Cellular Component	Nucleoplasm RNA Polymerase III Complex Cytosol	Endoplasmic Reticulum Lipid Droplet Cytosol
	Molecular Function	Double-stranded DNA Binding DNA-directed 5'-3' RNA Polymerase Activity Protein Binding	Ubiquitin-protein Transferase Activity Protein Binding ATP Binding Identical Protein Binding Ubiquitin Conjugating Enzyme Activity
	Biological Process	Regulation Of Transcription By RNA Polymerase III Transcription By RNA Polymerase III Positive Regulation Of Type I Interferon Production Positive Regulation Of Interferon-beta Production Innate Immune Response Positive Regulation Of Innate Immune Response Defense Response To Virus	Protein Polyubiquitination Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Ubiquitin-dependent ERAD Pathway Cellular Response To Interferon-beta Cellular Protein Catabolic Process Protein K48-linked Ubiquitination Negative Regulation Of Retrograde Protein Transport, ER To Cytosol
Pathways		Cytosolic sensors of pathogen-associated DNA RNA Polymerase III Chain Elongation RNA Polymerase III Transcription Termination RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter	Synthesis of active ubiquitin: roles of E1 and E2 enzymes Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Refractive error ( 32231278)
Interacting Genes		15 interacting genes: ATPAF2 BDP1 BRF1 ERG28 GTF3C4 KAT5 LRIF1 PRPF4B RIN3 STC2 SUV39H2 TBP TNS2 UBE2G2 WDR89	39 interacting genes: AMFR ARL14 AUP1 BIRC8 CBL CNNM3 CPOX CUL9 ECPAS FARP2 HBS1L KDM2A MDM2 MGRN1 MLLT6 MUL1 NDUFS4 POLR3F PRKN RBX1 RC3H1 RC3H2 RFFL RNF111 RNF146 RNF157 RNF168 RNF26 RNF5 TMEM45B TRIM3 TRIM43 UBA1 UBA6 UBC UBE2J2 UBE3A VAMP8 ZNRF4
Entrez ID		10621	7327
HPRD ID		15156	04387
Ensembl ID		ENSG00000132664	ENSG00000184787
Uniprot IDs		Q05DB8 Q9H1D9	P60604
PDB IDs		2DK5 2YU3	2CYX 2KLY 2LXP 3H8K 4LAD
Enriched GO Terms of Interacting Partners?
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