HIPK3 and TOX4

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		HIPK3	TOX4
Description		homeodomain interacting protein kinase 3	TOX high mobility group box family member 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Plasma Membrane Nuclear Body PML Body	Chromosome, Telomeric Region Chromatin Nucleus PTW/PP1 Phosphatase Complex
	Molecular Function	Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Tyrosine Kinase Activity ATP Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity	Protein Binding Chromatin DNA Binding
	Biological Process	Protein Phosphorylation Apoptotic Process MRNA Transcription Peptidyl-serine Phosphorylation Peptidyl-threonine Phosphorylation Peptidyl-tyrosine Phosphorylation Negative Regulation Of Apoptotic Process Negative Regulation Of JUN Kinase Activity	Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs		Fostamatinib
Diseases
GWAS		Anger ( 24489884) Obese vs. thin ( 30677029) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
Interacting Genes		37 interacting genes: AR ARRB2 C1QA CREB1 CREBBP DAXX FADD FAS FLNC GLUL GORASP1 GRB2 HEYL HNRNPA1 HNRNPA2B1 HNRNPH1 LIMD1 LIMK2 LIMS2 MBD1 MTMR4 NR2F2 RGS3 SIAH1 SIAH2 SKIL SNIP1 SRSF1 SRSF5 SUMO1 TGFB1I1 TOX4 TP73 TRA2B UBE2I ZNF107 ZYX	16 interacting genes: ATXN1 BANP CCBE1 CREB1 EXOSC10 FNDC3B GEMIN6 HIPK3 HSPB1 MYL7 PPP1CA QRICH1 TBX6 WDR82 ZMYND19 ZNF512B
Entrez ID		10114	9878
HPRD ID		05111	12661
Ensembl ID		ENSG00000110422	ENSG00000092203
Uniprot IDs		A8KAE4 Q9H422	O94842
PDB IDs
Enriched GO Terms of Interacting Partners?
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