HIPK3 and ZNF107

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		HIPK3	ZNF107
Description		homeodomain interacting protein kinase 3	zinc finger protein 107
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Plasma Membrane Nuclear Body PML Body	Cellular_component Nucleus
	Molecular Function	Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Tyrosine Kinase Activity ATP Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Molecular_function Protein Binding Metal Ion Binding
	Biological Process	Protein Phosphorylation Apoptotic Process MRNA Transcription Peptidyl-serine Phosphorylation Peptidyl-threonine Phosphorylation Peptidyl-tyrosine Phosphorylation Negative Regulation Of Apoptotic Process Negative Regulation Of JUN Kinase Activity	Regulation Of Transcription By RNA Polymerase II Biological_process Positive Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs		Fostamatinib
Diseases
GWAS		Anger ( 24489884) Obese vs. thin ( 30677029) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)	Metabolite levels ( 23823483)
Interacting Genes		37 interacting genes: AR ARRB2 C1QA CREB1 CREBBP DAXX FADD FAS FLNC GLUL GORASP1 GRB2 HEYL HNRNPA1 HNRNPA2B1 HNRNPH1 LIMD1 LIMK2 LIMS2 MBD1 MTMR4 NR2F2 RGS3 SIAH1 SIAH2 SKIL SNIP1 SRSF1 SRSF5 SUMO1 TGFB1I1 TOX4 TP73 TRA2B UBE2I ZNF107 ZYX	5 interacting genes: HIPK3 HOOK2 KRTAP10-8 SMAD7 U2AF2
Entrez ID		10114	51427
HPRD ID		05111	18669
Ensembl ID		ENSG00000110422	ENSG00000196247
Uniprot IDs		A8KAE4 Q9H422	A0A024R5Y9 A0A087WYK5 A0A0B4J2G0 Q8WVL4 Q9UII5
PDB IDs
Enriched GO Terms of Interacting Partners?
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