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SCAP

Description SREBF chaperone
Image No pdb structure
GO Annotations Cellular Component
  • Golgi Membrane
  • Endoplasmic Reticulum
  • Endoplasmic Reticulum Membrane
  • Golgi Apparatus
  • ER To Golgi Transport Vesicle Membrane
  • Integral Component Of Membrane
  • Protein-containing Complex
Molecular Function
  • Protein Binding
  • Sterol Binding
  • Protein-containing Complex Binding
  • Unfolded Protein Binding
Biological Process
  • Response To Hypoxia
  • Immune Response
  • Aging
  • Cholesterol Metabolic Process
  • Response To Insulin
  • SREBP Signaling Pathway
  • Regulation Of Fatty Acid Biosynthetic Process
  • Cellular Lipid Metabolic Process
  • Negative Regulation Of Cholesterol Biosynthetic Process
  • Positive Regulation Of Cholesterol Biosynthetic Process
  • COPII-coated Vesicle Cargo Loading
Pathways
  • Regulation of cholesterol biosynthesis by SREBP (SREBF)
  • Regulation of cholesterol biosynthesis by SREBP (SREBF)
Drugs
Diseases
GWAS
  • Refractive error ( 32231278)
  • Triglyceride levels ( 32203549)
Novel Interacting Genes 7 novel interacting genes: ATG16L1 DHX30 HIPK2 KLHL18 LAMC2 NDUFAF3 WDR6
Interacting Genes 5 interacting genes: INSIG1 INSIG2 PGRMC1 SEC24B SREBF2
Entrez ID 22937
HPRD ID 03300
Ensembl ID ENSG00000114650
Uniprot IDs B7Z6H0 Q12770
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025