SCAP and KLHL18

Data Source:
BioGRID (affinity chromatography technology)

		SCAP	KLHL18
Description		SREBF chaperone	kelch like family member 18
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus ER To Golgi Transport Vesicle Membrane Integral Component Of Membrane Protein-containing Complex
	Molecular Function	Protein Binding Sterol Binding Protein-containing Complex Binding Unfolded Protein Binding	Protein Binding
	Biological Process	Response To Hypoxia Immune Response Aging Cholesterol Metabolic Process Response To Insulin SREBP Signaling Pathway Regulation Of Fatty Acid Biosynthetic Process Cellular Lipid Metabolic Process Negative Regulation Of Cholesterol Biosynthetic Process Positive Regulation Of Cholesterol Biosynthetic Process COPII-coated Vesicle Cargo Loading	Cell Cycle Protein Ubiquitination Cell Division Positive Regulation Of Mitotic Cell Cycle Phase Transition
Pathways		Regulation of cholesterol biosynthesis by SREBP (SREBF) Regulation of cholesterol biosynthesis by SREBP (SREBF)
Drugs
Diseases
GWAS		Refractive error ( 32231278) Triglyceride levels ( 32203549)	Huntington's disease progression ( 28642124) Refractive error ( 32231278)
Interacting Genes		5 interacting genes: INSIG1 INSIG2 PGRMC1 SEC24B SREBF2	2 interacting genes: AURKA EEF1G
Entrez ID		22937	23276
HPRD ID		03300	10017
Ensembl ID		ENSG00000114650	ENSG00000114648
Uniprot IDs		B7Z6H0 Q12770	A0A024R2T4 B4DHW4 O94889
PDB IDs
Enriched GO Terms of Interacting Partners?
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