CYP27B1

Description		cytochrome P450 family 27 subfamily B member 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Mitochondrial Outer Membrane
	Molecular Function	Calcidiol 1-monooxygenase Activity Iron Ion Binding Heme Binding Secalciferol 1-monooxygenase Activity
	Biological Process	Vitamin Metabolic Process Calcium Ion Transport Negative Regulation Of Cell Population Proliferation Negative Regulation Of Calcidiol 1-monooxygenase Activity Positive Regulation Of Vitamin D 24-hydroxylase Activity Bone Mineralization Negative Regulation Of Cell Growth Regulation Of Bone Mineralization Response To Lipopolysaccharide Response To Vitamin D Response To Interferon-gamma Calcitriol Biosynthetic Process From Calciol Vitamin D Metabolic Process Vitamin D Catabolic Process Response To Estrogen Positive Regulation Of Keratinocyte Differentiation Decidualization Calcium Ion Homeostasis G1 To G0 Transition Positive Regulation Of Vitamin D Receptor Signaling Pathway
Pathways		Vitamin D (calciferol) metabolism Vitamins Defective CYP27B1 causes Rickets vitamin D-dependent 1A (VDDR1A)
Drugs		Alfacalcidol
Diseases		Type I diabetes mellitus
GWAS		Brain morphology (MOSTest) ( 32665545) Multiple sclerosis ( 19525955 21833088)
Novel Interacting Genes		8 novel interacting genes: ATF2 HOXC10 ITGB7 MARS1 MYL6 SMC3 TMEM50B TUT4
Interacting Genes
Entrez ID		1594
HPRD ID		02031
Ensembl ID		ENSG00000111012
Uniprot IDs		O15528
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?