MAFB and FOSL1

Number of citations of the paper that reports this interaction (PubMedID 23661758)
49

Data Source:
BioGRID (fluorescent resonance energy transfer)

		MAFB	FOSL1
Description		MAF bZIP transcription factor B	FOS like 1, AP-1 transcription factor subunit
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Transcription Factor Complex	Nuclear Chromatin Nucleus Nucleoplasm Cytosol Presynaptic Membrane Neuron Projection
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Transcription Factor Binding Identical Protein Binding Sequence-specific DNA Binding Protein-containing Complex Binding	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding
	Biological Process	Regulation Of Transcription, DNA-templated Segment Specification Sensory Organ Development Respiratory Gaseous Exchange Rhombomere 5 Development Rhombomere 6 Development Abducens Nerve Formation T Cell Differentiation In Thymus Brain Segmentation Inner Ear Morphogenesis Negative Regulation Of Erythrocyte Differentiation Negative Regulation Of Osteoclast Differentiation Positive Regulation Of Transcription By RNA Polymerase II Thymus Development	In Utero Embryonic Development Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Chemotaxis Cellular Defense Response Vitellogenesis Female Pregnancy Learning Positive Regulation Of Cell Proliferation Negative Regulation Of Cell Proliferation Response To Mechanical Stimulus Response To Virus Response To Gravity Cellular Response To Extracellular Stimulus Response To Progesterone Response To Cytokine Response To Hydrogen Peroxide Positive Regulation Of Apoptotic Process Positive Regulation Of Cell Cycle Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of DNA-binding Transcription Factor Activity Response To Corticosterone Response To CAMP Placenta Blood Vessel Development Pri-miRNA Transcription By RNA Polymerase II Positive Regulation Of DNA-templated Transcription, Initiation
Pathways		Activation of anterior HOX genes in hindbrain development during early embryogenesis	NGF-stimulated transcription
Drugs
Diseases
GWAS		Birth weight ( 31043758 27680694) Bone mineral density (hip) ( 30172743) Cholesterol, total ( 24097068 25961943 20686565) Cleft lip with or without cleft palate ( 28054174) Cognitive decline rate in late mild cognitive impairment ( 26252872) Drug-induced Stevens-Johnson syndrome or toxic epidermal necrolysis (SJS/TEN) ( 21221126) Dupuytren's disease ( 28886342 21732829) Height ( 25282103) LDL cholesterol ( 24097068 19060906 25961943 20686565) LDL cholesterol levels ( 28334899) Metabolite levels (lipoprotein measures) ( 27005778) Nonsyndromic cleft lip ( 31609978) Nonsyndromic cleft lip with cleft palate ( 28232668) Nonsyndromic cleft lip with or without cleft palate ( 25775280) Obesity-related traits ( 23251661) Orofacial clefts ( 28054174) Paneth cell defects in Crohn's disease ( 28352666) Plasma parathyroid hormone levels ( 30134803) QT interval (ambient particulate matter interaction) ( 28749367) Response to TNF antagonist treatment ( 18615156) Serum total protein level ( 29403010) Total body bone mineral density ( 29304378)	Acne (severe) ( 24927181) Eosinophil counts ( 27863252) Eosinophil percentage of white cells ( 27863252) Inflammatory bowel disease ( 23128233) Psoriasis ( 28537254) Sum eosinophil basophil counts ( 27863252)
Interacting Genes		11 interacting genes: ATF4 BACH1 DDB1 FOS FOSL1 HOXD12 JUN MAF ZDHHC2 ZFP64 ZWINT	24 interacting genes: ATF2 ATF3 ATF4 ATXN1 CALCOCO1 CEBPA CEBPE CEBPG CREB5 DDIT3 DNMT3L EP300 JUN JUNB KPNA1 LDOC1 MAF MAFB NME7 PARVG TAB2 TRIM24 USF1 WFDC1
Entrez ID		9935	8061
HPRD ID		07129	00643
Ensembl ID		ENSG00000204103	ENSG00000175592
Uniprot IDs		Q9Y5Q3	A0A0S2Z595 E9PKL5 E9PPX2 P15407
PDB IDs
Enriched GO Terms of Interacting Partners?
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