MAFB and ZDHHC2

Number of citations of the paper that reports this interaction (PubMedID 20211142)
329

Data Source:
BioGRID (two hybrid)

		MAFB	ZDHHC2
Description		MAF bZIP transcription factor B	zinc finger DHHC-type palmitoyltransferase 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Transcription Factor Complex	Endoplasmic Reticulum Golgi Apparatus Plasma Membrane Integral Component Of Plasma Membrane Recycling Endosome Membrane
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Transcription Factor Binding Identical Protein Binding Sequence-specific DNA Binding Protein-containing Complex Binding	Palmitoyltransferase Activity Protein-cysteine S-palmitoyltransferase Activity
	Biological Process	Regulation Of Transcription, DNA-templated Segment Specification Sensory Organ Development Respiratory Gaseous Exchange Rhombomere 5 Development Rhombomere 6 Development Abducens Nerve Formation T Cell Differentiation In Thymus Brain Segmentation Inner Ear Morphogenesis Negative Regulation Of Erythrocyte Differentiation Negative Regulation Of Osteoclast Differentiation Positive Regulation Of Transcription By RNA Polymerase II Thymus Development	Protein Targeting To Membrane Peptidyl-L-cysteine S-palmitoylation Protein Palmitoylation Cellular Protein Metabolic Process
Pathways		Activation of anterior HOX genes in hindbrain development during early embryogenesis	Surfactant metabolism
Drugs
Diseases
GWAS		Birth weight ( 31043758 27680694) Bone mineral density (hip) ( 30172743) Cholesterol, total ( 24097068 25961943 20686565) Cleft lip with or without cleft palate ( 28054174) Cognitive decline rate in late mild cognitive impairment ( 26252872) Drug-induced Stevens-Johnson syndrome or toxic epidermal necrolysis (SJS/TEN) ( 21221126) Dupuytren's disease ( 28886342 21732829) Height ( 25282103) LDL cholesterol ( 24097068 19060906 25961943 20686565) LDL cholesterol levels ( 28334899) Metabolite levels (lipoprotein measures) ( 27005778) Nonsyndromic cleft lip ( 31609978) Nonsyndromic cleft lip with cleft palate ( 28232668) Nonsyndromic cleft lip with or without cleft palate ( 25775280) Obesity-related traits ( 23251661) Orofacial clefts ( 28054174) Paneth cell defects in Crohn's disease ( 28352666) Plasma parathyroid hormone levels ( 30134803) QT interval (ambient particulate matter interaction) ( 28749367) Response to TNF antagonist treatment ( 18615156) Serum total protein level ( 29403010) Total body bone mineral density ( 29304378)	Diastolic blood pressure response to hydrochlorothiazide in hypertension ( 27802415) Schizophrenia ( 28991256 30285260) Systolic blood pressure response to hydrochlorothiazide in hypertension ( 27802415)
Interacting Genes		11 interacting genes: ATF4 BACH1 DDB1 FOS FOSL1 HOXD12 JUN MAF ZDHHC2 ZFP64 ZWINT	2 interacting genes: MAFB MSX2
Entrez ID		9935	51201
HPRD ID		07129	15715
Ensembl ID		ENSG00000204103	ENSG00000104219
Uniprot IDs		Q9Y5Q3	A0A140VKD9 Q9UIJ5
PDB IDs
Enriched GO Terms of Interacting Partners?
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