SFI1 and CCDC120

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		SFI1	CCDC120
Description		SFI1 centrin binding protein	coiled-coil domain containing 120
Image			No pdb structure
GO Annotations	Cellular Component	Centrosome Centriole Cytosol	Endosome Centriole Growth Cone Centriolar Subdistal Appendage
	Molecular Function	Protein Binding Phosphatase Binding	Protein Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Regulation Of G2/M Transition Of Mitotic Cell Cycle Negative Regulation Of Phosphatase Activity Ciliary Basal Body-plasma Membrane Docking	Multicellular Organism Development Protein Localization Microtubule Anchoring At Centrosome
Pathways		Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2
Drugs
Diseases
GWAS		Age-related hearing impairment ( 24939585) Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL) ( 28090653) Metabolite levels ( 23823483) Type 2 diabetes ( 31118516)
Interacting Genes		14 interacting genes: CCDC120 CCDC57 CETN2 CRX FAM131C GCSH GOLGA2 KRT19 LPXN MAD2L2 MDFI RADIL RBPMS SERTAD1	19 interacting genes: BRCA1 CCDC102B CCDC57 CCDC85B CEP170P1 CYTH2 DAZAP2 EFHC2 KRT15 KRT31 KRT40 LMNA MDFI MID2 SFI1 SMARCB1 TRAF1 USHBP1 ZDHHC17
Entrez ID		9814	90060
HPRD ID		11550	06595
Ensembl ID		ENSG00000198089	ENSG00000147144
Uniprot IDs		A8K8P3	Q96HB5
PDB IDs		2K2I
Enriched GO Terms of Interacting Partners?
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